Objectives COVID-19 is a transmissible illness triggered by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). Since its onset in late 2019 in Wuhan city of China …

Apicomplexans are a diverse and complex group of protozoan pathogens including
Toxoplasma gondii, Plasmodium spp., Cryptosporidium spp., Eimeria spp., and Babesia …

Background Severe malaria (SM) is a fatal multi-system disease which accounted for an
estimated 619,000 deaths in 2021. Less than 30% of children presenting with SM are …

Significant selection pressure has been exerted on the genomes of human populations
exposed to Plasmodium falciparum infection, resulting in the acquisition of mechanisms of …

Every year, millions of people are infected with malaria, resulting in significant economic
losses to the developing and developed nations. The malaria parasite pursues a …

South and Southeast Asia and Latin American together comprise 46 countries and are home
to approximately 40% of the world population. The sociopolitical and economic …

Malaria is a disease that affects thousands of people around the world every year. Its
pathogenesis is associated with the production of reactive oxygen and nitrogen species …

Malaria remains a serious threat to global health. Sustained malaria control and, eventually,
eradication will only be achieved with a broadly effective malaria vaccine. Yet a fundamental …

Inflammatory responses to hemin are believed to play an important role in tissue damage
and cerebral malaria pathology. Macrophage exposed to hemin exhibits modulation of non …

Background Cerebral malaria (CM) is a fatal neuroinflammatory syndrome caused (in
humans) by the protozoa Plasmodium (P.) falciparum. Glial cell activation is one of the …