Navigating multi-scale cancer systems biology towards model-driven clinical oncology and its applications in personalized therapeutics
MN Gondal, SU Chaudhary - Frontiers in Oncology, 2021 - frontiersin.org
Rapid advancements in high-throughput omics technologies and experimental protocols
have led to the generation of vast amounts of scale-specific biomolecular data on cancer …
have led to the generation of vast amounts of scale-specific biomolecular data on cancer …
Withanolide A offers neuroprotection, ameliorates stress resistance and prolongs the life expectancy of Caenorhabditis elegans
Withanolide A (steroidal lactone) forms the major constituent of the most popular herbal drug
in Ayurvedic medicine, Ashwagandha. It has been used since ancient times as an …
in Ayurvedic medicine, Ashwagandha. It has been used since ancient times as an …
Designing of Complex Multi-epitope Peptide Vaccine Based on Omps of Klebsiella pneumoniae: An In Silico Approach
Klebsiella pneumoniae is a hospital-acquired pathogen that leads to various infections.
There is a great interest in developing an efficient Klebsiella vaccine and epitope-based …
There is a great interest in developing an efficient Klebsiella vaccine and epitope-based …
Genome-wide scan for potential CD4+ T-cell vaccine candidates in Candida auris by exploiting reverse vaccinology and evolutionary information
SK Gupta, Ö Osmanoglu, R Minocha, SR Bandi… - Frontiers in …, 2022 - frontiersin.org
Candida auris is a globally emerging fungal pathogen responsible for causing nosocomial
outbreaks in healthcare associated settings. It is known to cause infection in all age groups …
outbreaks in healthcare associated settings. It is known to cause infection in all age groups …
In silico designing a candidate vaccine against breast cancer
Breast cancer (BC) is the most common type of women's cancer with a prevalence of about
25%, although it is rare in men (< 1%). Until now, BC therapy approaches have not been …
25%, although it is rare in men (< 1%). Until now, BC therapy approaches have not been …
Understanding the Mechanism of Atovaquone Drug Resistance in Plasmodium falciparum Cytochrome b Mutation Y268S Using Computational Methods
The rapid appearance of resistant malarial parasites after introduction of atovaquone (ATQ)
drug has prompted the search for new drugs as even single point mutations in the active site …
drug has prompted the search for new drugs as even single point mutations in the active site …
Designing and Modeling of Complex DNA Vaccine Based on Tropomyosin Protein of Boophilus Genus Tick
Boophilus tick is a bloodsucking ectoparasite that transfers some pathogens, reducing
production and thus leading to economical losses in the cattle industry. Tropomyosin (TPM) …
production and thus leading to economical losses in the cattle industry. Tropomyosin (TPM) …
[HTML][HTML] In silico evaluation of two targeted chimeric proteins based on bacterial toxins for breast cancer therapy
Background: Despite major advances in cancer research, breast cancer still remains the
most common cancer in women. Breast cancer is a heterogeneous disease, including at …
most common cancer in women. Breast cancer is a heterogeneous disease, including at …
Designing of an epitope-based peptide vaccine against walking pneumonia: an immunoinformatics approach
Mycoplasma pneumoniae is a substantial respiratory pathogen that develops not only
pneumonia but also other respiratory diseases, which mimic viral respiratory syndromes …
pneumonia but also other respiratory diseases, which mimic viral respiratory syndromes …
An antibiotic target ranking and prioritization pipeline combining sequence, structure and network-based approaches exemplified for Serratia marcescens
We investigate a drug target screening pipeline comparing sequence, structure and network-
based criteria for prioritization. Serratia marcescens, an opportunistic pathogen, serves as …
based criteria for prioritization. Serratia marcescens, an opportunistic pathogen, serves as …