With the current treatment regimens, many patients with acute myeloid leukemia (AML) will
achieve a morphologic complete remission (CR) with the morphologic bone marrow (BM) …

Abstract Purpose of Review Acute lymphoblastic leukemias (ALL) are malignant disorders of
immature B or T cells that occur characteristically in children, usually under the age of 6 …

Hemophagocytic lymphohistiocytosis (HLH) is characterized by hyperinflammation and
multiorgan dysfunction. Infections, including the reactivation of viruses, contribute to …

Background Multiparametric flow cytometry (MFC) is an essential diagnostic tool in B acute
lymphoblastic leukemia (B ALL) to determine the B‐lineage affiliation of the blast population …

Introduction The discrimination of leukemia lymphoblasts (LB) in diagnosis and follow‐up of
B‐cell progenitor acute lymphoblastic leukemia (BCP‐ALL) by multiparameter flow …

Background Recent studies have demonstrated hematogones (HGs) expansion to be
associated with favorable outcomes in hematological diseases, especially in patients with …

B-cell acute lymphoblastic leukemia (B-ALL) is a hematologic malignancy of B-type
lymphoid precursor cells. Minimal/measurable residual disease (MRD) is an important …

Background Immunophenotyping is a valuable ancillary technique for the differential
diagnosis between myelodysplastic syndromes (MDS) with low bone marrow (BM) blast …

Lymphoid aggregates in bone marrow specimens are a relatively frequent finding that may
pose a diagnostic challenge for a pathologist. The distinction between reactive and …

Amidst the genomic revolution in the characterization of the acute leukemias,
immunophenotyping maintains a crucial position in diagnosis, determination of therapy, and …