The concept of the exposome was introduced over 15 years ago to reflect the important role
that the environment exerts on health and disease. While originally viewed as a call-to-arms …

The development of the exposome concept has been one of the hallmarks of environmental
and health research for the last decade. The exposome encompasses the life course …

Metabolomics describes a high-throughput approach for measuring a repertoire of
metabolites and small molecules in biological samples. One utility of untargeted …

Organisms are exposed to ever‐changing complex mixtures of chemicals over the course of
their lifetime. The need to more comprehensively describe this exposure and relate it to …

The exposome concept encourages holistic consideration of the non-genetic factors
(environmental exposures including lifestyle) that influence an individual's health over their …

The rising use of pesticides in modern agriculture has led to a shift in disease burden in
which exposure to these chemicals plays an increasingly important role. The human gut …

Background There is emerging evidence that air pollution exposure increases the risk of
developing liver cancer. To date, there have been four epidemiologic studies conducted in …

This paper explores the exposome concept and its role in elucidating the interplay between
environmental exposures and human health. We introduce two key concepts critical for …

The worldwide prevalence of allergic disease is rising as a result of complex gene-
environment interactions that shape the immune system and host response. Climate change …

Humans are exposed to a cocktail of food-related and environmental contaminants,
potentially contributing to the etiology of chronic diseases. Better characterizing the …