The health digital twin: advancing precision cardiovascular medicine

G Coorey, GA Figtree, DF Fletcher… - Nature Reviews …, 2021 - nature.com
Precision medicine envisages a changed paradigm for health care through better
understanding of individual disease susceptibility and prognosis, enabling more …

Clinical Pathway for Coronary Atherosclerosis in Patients Without Conventional Modifiable Risk Factors: JACC State-of-the-Art Review

GA Figtree, ST Vernon, JA Harmer, MP Gray… - Journal of the American …, 2023 - jacc.org
Reducing the incidence and prevalence of standard modifiable cardiovascular risk factors
(SMuRFs) is critical to tackling the global burden of coronary artery disease (CAD) …

Mortality in STEMI patients without standard modifiable risk factors: a sex-disaggregated analysis of SWEDEHEART registry data

GA Figtree, ST Vernon, N Hadziosmanovic… - The Lancet, 2021 - thelancet.com
Background In cardiovascular disease, prevention strategies targeting standard modifiable
cardiovascular risk factors (SMuRFs; hypertension, diabetes, hypercholesterolaemia, and …

Higher mortality in acute coronary syndrome patients without standard modifiable risk factors: results from a global meta-analysis of 1,285,722 patients

G Kong, YH Chin, B Chong, RSJ Goh, OZH Lim… - International Journal of …, 2023 - Elsevier
Background Standard modifiable cardiovascular risk factors (SMuRF), comprising diabetes,
hyperlipidemia, hypertension, and smoking, are used for risk stratification in acute coronary …

A call to action for new global approaches to cardiovascular disease drug solutions

GA Figtree, K Broadfoot, B Casadei, R Califf… - European heart …, 2021 - academic.oup.com
Whilst we continue to wrestle with the immense challenge of implementing equitable access
to established evidence-based treatments, substantial gaps remain in our pharmacotherapy …

Prognostic outcomes in acute myocardial infarction patients without standard modifiable risk factors: a multiethnic study of 8,680 Asian patients

G Kong, NWS Chew, CH Ng, YH Chin… - Frontiers in …, 2022 - frontiersin.org
Background An increasing proportion of patients with acute myocardial infarction (AMI) are
presenting without standard modifiable risk factors (SMuRFs) of hypertension …

Noninvasive plaque imaging to accelerate coronary artery disease drug development

GA Figtree, PD Adamson, C Antoniades… - Circulation, 2022 - Am Heart Assoc
Coronary artery disease (CAD) remains the leading cause of adult mortality globally.
Targeting known modifiable risk factors has had substantial benefit, but there remains a …

[HTML][HTML] Same script, different viruses: HIV and COVID-19 in US Black communities

EL Fields, R Copeland, E Hopkins - The Lancet, 2021 - thelancet.com
The initial US response to both HIV and COVID-19 underestimated the risk to the general
population and focused instead on the specific populations in which infections first emerged …

Comparison of mortality outcomes in acute myocardial infarction patients with or without standard modifiable cardiovascular risk factors

CH Sia, J Ko, H Zheng, AFW Ho, D Foo… - Frontiers in …, 2022 - frontiersin.org
Background Acute myocardial infarction (AMI) cases have decreased in part due to the
advent of targeted therapies for standard modifiable cardiovascular disease risk factors …

Hepatic steatosis and advanced hepatic fibrosis are independent predictors of long‐term mortality in acute myocardial infarction

YH Chin, J Lim, G Kong, CH Ng, R Goh… - Diabetes, Obesity …, 2023 - Wiley Online Library
Aim To examine the prevalence and prognosis of hepatic steatosis and fibrosis in post‐
acute myocardial infarction (AMI) patients. Methods Patients presenting with AMI to a tertiary …