Epigenetics in cancer stem cells

TB Toh, JJ Lim, EKH Chow - Molecular cancer, 2017 - Springer
Compelling evidence have demonstrated that bulk tumors can arise from a unique subset of
cells commonly termed “cancer stem cells” that has been proposed to be a strong driving …

Epigenetic heterogeneity in cancer

M Guo, Y Peng, A Gao, C Du, JG Herman - Biomarker research, 2019 - Springer
Phenotypic and functional heterogeneity is one of the hallmarks of human cancers. Tumor
genotype variations among tumors within different patients are known as interpatient …

Gastric cancer: advances in carcinogenesis research and new therapeutic strategies

L Seeneevassen, E Bessède, F Mégraud… - International journal of …, 2021 - mdpi.com
Gastric cancer's bad incidence, prognosis, cellular and molecular heterogeneity amongst
others make this disease a major health issue worldwide. Understanding this affliction is a …

[HTML][HTML] Molecular classification of gastric cancer

NY Chia, P Tan - Annals of Oncology, 2016 - Elsevier
Gastric cancer (GC), a heterogeneous disease characterized by epidemiologic and
histopathologic differences across countries, is a leading cause of cancer-related death …

[HTML][HTML] Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review

MA Chiurillo - World journal of experimental medicine, 2015 - ncbi.nlm.nih.gov
Gastric cancer remains one of the most common cancers worldwide and one of the leading
cause for cancer-related deaths. Gastric adenocarcinoma is a multifactorial disease that is …

Advances in understanding how heavy metal pollution triggers gastric cancer

W Yuan, N Yang, X Li - BioMed research international, 2016 - Wiley Online Library
With the development of industrialization and urbanization, heavy metals contamination has
become a major environmental problem. Numerous investigations have revealed an …

Future cancer research priorities in the USA: a Lancet Oncology Commission

EM Jaffee, C Van Dang, DB Agus… - The Lancet …, 2017 - thelancet.com
We are in the midst of a technological revolution that is providing new insights into human
biology and cancer. In this era of big data, we are amassing large amounts of information …

How to stomach an epigenetic insult: the gastric cancer epigenome

N Padmanabhan, T Ushijima, P Tan - Nature reviews Gastroenterology …, 2017 - nature.com
Gastric cancer is a deadly malignancy afflicting close to a million people worldwide. Patient
survival is poor and largely due to late diagnosis and suboptimal therapies. Disease …

[HTML][HTML] Tumor heterogeneity of gastric cancer: From the perspective of tumor-initiating cell

JP Gao, W Xu, WT Liu, M Yan… - World Journal of …, 2018 - ncbi.nlm.nih.gov
Gastric cancer (GC) remains one of the most common and malignant types of cancer due to
its rapid progression, distant metastasis, and resistance to conventional chemotherapy …

Precancer atlas to drive precision prevention trials

A Spira, MB Yurgelun, L Alexandrov, A Rao, R Bejar… - Cancer research, 2017 - AACR
Cancer development is a complex process driven by inherited and acquired molecular and
cellular alterations. Prevention is the holy grail of cancer elimination, but making this a reality …