Survivin, a member of the inhibitor of apoptosis (IAP) protein family that inhibits caspases
and blocks cell death, is highly expressed in most cancers and is associated with a poor …

Acquisition of the ability to evade cellular suicide, or apoptosis, is one of the master switches
that contributes to cellular transformation and, ultimately, to invasive cancer. Much has been …

Survivin is a member of the inhibitor of apoptosis (IAP) gene family that has attracted
attention from several viewpoints of basic and translational research. Its cell cycle-regulated …

Apoptosis is a highly regulated process of cell deletion and plays a fundamental role in the
maintenance of tissue homeostasis in the adult organism. Numerous studies in recent years …

The inhibitor of apoptosis proteins (IAPs) are a family of antiapoptotic proteins that bind and
inhibit caspases 3, 7, and/or 9, but not caspase 8. Growing evidence also indicates that IAPs …

Various accumulating evidence suggests that survivin, a member of the inhibitor of
apoptosis (IAP) family, plays an important role in drug resistance and cancer cell survival in …

Survivin, an inhibitor of apoptosis protein, is highly expressed in most cancers and
associated with chemotherapy resistance, increased tumor recurrence, and shorter patient …

Colorectal cancer (CRC) is one of the most prevalent cancers, with more than one million
new cases every year. In the last few decades, several advancements in therapeutic and …

Microtubules are dynamic polymers that play crucial roles in a large number of cellular
functions. Their pivotal role in mitosis makes them a target for the development of anticancer …

The transcription factor nuclear factor kappa B (NF-κB) has attracted increasing attention in
the field of cancer research from last few decades. Aberrant activation of this transcription …