[HTML][HTML] Molecular mechanism of interaction between SARS-CoV-2 and host cells and interventional therapy

Q Zhang, R Xiang, S Huo, Y Zhou, S Jiang… - Signal transduction and …, 2021 - nature.com
The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …

[HTML][HTML] mRNA vaccines for COVID-19: what, why and how

JW Park, PNP Lagniton, Y Liu… - International journal of …, 2021 - ncbi.nlm.nih.gov
Abstract The Coronavirus disease-19 (COVID-19) pandemic, caused by severe acute
respiratory syndrome coronavirus-2 (SARS-CoV-2), has impacted human lives in the most …

Obesity and diabetes as high‐risk factors for severe coronavirus disease 2019 (Covid‐19)

Y Zhou, J Chi, W Lv, Y Wang - Diabetes/metabolism research …, 2021 - Wiley Online Library
The outbreak of the coronavirus disease 2019 (Covid‐19) has become an evolving
worldwide health crisis. With the rising prevalence of obesity and diabetes has come an …

Diabetes in COVID-19: Prevalence, pathophysiology, prognosis and practical considerations

AK Singh, R Gupta, A Ghosh, A Misra - Diabetes & Metabolic Syndrome …, 2020 - Elsevier
Background and aims High prevalence of diabetes makes it an important comorbidity in
patients with COVID-19. We sought to review and analyze the data regarding the …

[HTML][HTML] Comorbidities and the risk of severe or fatal outcomes associated with coronavirus disease 2019: A systematic review and meta-analysis

Y Zhou, Q Yang, J Chi, B Dong, W Lv, L Shen… - International Journal of …, 2020 - Elsevier
Objectives Existing findings regarding the relationship between comorbidities and the
severity of coronavirus disease 2019 (COVID-19) are inconsistent and insufficient. The aim …

[HTML][HTML] ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities

N Zamorano Cuervo, N Grandvaux - elife, 2020 - elifesciences.org
Pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes
coronavirus 19 disease (COVID-19) which presents a large spectrum of manifestations with …

[HTML][HTML] Hypertension, thrombosis, kidney failure, and diabetes: is COVID-19 an endothelial disease? A comprehensive evaluation of clinical and basic evidence

C Sardu, J Gambardella, MB Morelli, X Wang… - Journal of clinical …, 2020 - mdpi.com
The symptoms most commonly reported by patients affected by coronavirus disease (COVID-
19) include cough, fever, and shortness of breath. However, other major events usually …

Use of renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study

FJ de Abajo, S Rodríguez-Martín, V Lerma… - The Lancet, 2020 - thelancet.com
Background Concerns have been raised about the possibility that inhibitors of the renin–
angiotensin–aldosterone system (RAAS) could predispose individuals to severe COVID-19; …

[HTML][HTML] Endocrine and metabolic link to coronavirus infection

SR Bornstein, R Dalan, D Hopkins… - Nature Reviews …, 2020 - nature.com
Type 2 diabetes mellitus and hypertension are the most common comorbidities in patients
with coronavirus infections. Emerging evidence demonstrates an important direct metabolic …

[HTML][HTML] ACE2, much more than just a receptor for SARS-COV-2

L Samavati, BD Uhal - Frontiers in cellular and infection microbiology, 2020 - frontiersin.org
The rapidly evolving pandemic of severe acute respiratory syndrome coronavirus (SARS-
CoV-2) infection worldwide cost many lives. The angiotensin converting enzyme-2 (ACE-2) …