Adult hippocampal neurogenesis (AHN) drops sharply during early stages of Alzheimer's
disease (AD), via unknown mechanisms, and correlates with cognitive status in AD patients …

In the adult dentate gyrus of the hippocampus there are neuronal stem cells that give rise to
immature neurons and subsequently to mature functional granule neurons. The rate of …

The notion of exploiting the regenerative potential of the human brain in physiological aging
or neurological diseases represents a particularly attractive alternative to conventional …

Adult hippocampal neurogenesis (AHN) gives rise to new neurons throughout life. This
phenomenon takes place in more than 120 mammalian species, including humans, yet its …

Electroconvulsive therapy (ECT) is an effective therapy for depression, but its cellular effects
on the human brain remain elusive. In rodents, electroconvulsive shocks increase …

The primate hippocampus includes the dentate gyrus, cornu ammonis (CA), and subiculum.
CA is subdivided into four fields (CA1-CA3, plus CA3h/hilus of the dentate gyrus) with …

In most mammals, new neurons are not only produced during embryogenesis but also after
birth. Soon after adult neurogenesis was discovered, the influence of recruiting new neurons …

Monocarboxylate transporter 8 (MCT8) and organic anion transporter polypeptide 1C1
(OATP1C1) are thyroid hormone (TH) transmembrane transporters that play an important …

This paper bridges critical gaps through proposing a novel, environmentally mediated brain-
derived neurotrophic factor (BDNF)-interactive model that promises to sustain adult …

As human longevity has increased, we have come to understand the ability of the brain to
function into advanced age, but also its vulnerability with age, apparent in the age-related …