The heat shock proteins (HSPs) are ubiquitous and conserved protein families in both
prokaryotic and eukaryotic organisms, and they maintain cellular proteostasis and protect …

Neutrophils are the most abundant circulating and first-responding innate myeloid cells and
have so far been underestimated in the context of multiple sclerosis (MS). MS is the most …

Background and Aims Acute-on-chronic liver failure (ACLF) is characterized by systemic
inflammation accompanied by defective anti-bacterial immunity. The role of neutrophils in …

Within the last two decades, there has been increasing evidence that heat-shock proteins
can have a differential influence on the immune system. They can either provoke or …

All living beings have an optimal temperature for growth and survival. With the advancement
of global warming, the search for understanding adaptive processes to climate changes has …

The function of oxidatively modified low-density lipoprotein (oxLDL) in the progression of
cardiovascular diseases has been extensively investigated and well-characterized with …

Neutrophils are essential to a healthy life, yet pose a threat if improperly controlled.
Neutrophil perversion is well documented in a variety of inflammatory disorders (eg arthritis …

The heat shock protein HSP27 has been correlated in ovarian cancer (OC) patients with
aggressiveness and chemoresistance and, therefore, represents a promising potential …

Background Fingolimod is a sphingosine 1-phosphate receptor modulator approved for
relapsing MS. Long-term effects on the immunological profile are not fully understood …

Mechanical damage on the skin not only affects barrier function but also induces various
immune responses, which trigger or exacerbate skin inflammation. However, how …