Disseminated tumor cells (DTCs) are known to enter a state of dormancy that is achieved via
growth arrest of DTCs and/or a form of population equilibrium state, strongly influenced by …

Several studies have shown that cancer cells can be “phenotypically reversed”, thus
achieving a “tumor reversion”, by losing malignant hallmarks as migrating and invasive …

The regenerative capacity varies significantly among the animal kingdom. Successful
regeneration program in some animals results in the functional restoration of tissues and lost …

Different experimental models reveal that malignant cancer cells can be induced to change
their phenotype into a benign one. This phenotypic transformation, confirmed both in vitro …

Simple Summary Radiation therapy for cancer treatment can lead to damage to surrounding
healthy tissues and organs, like salivary glands. Loss of salivary function leads to a …

Triple-negative breast cancer (TNBC) lacks estrogen, progesterone, and human epidermal
growth factor receptors and has a poor prognosis as it is resistant to chemotherapy. A new …

Many cells are capable of maintaining viability in a non-dividing state with minimal
metabolism under unfavorable conditions. These are germ cells, adult stem cells, and …

Reversion of tumor to a normal differentiated cell once considered a dream is now at the
brink of becoming a reality. Different layers of molecules/events such as microRNAs …

Tumour cell dormancy is critical for metastasis and resistance to chemoradiotherapy.
Polyploid giant cancer cells (PGCCs) with giant or multiple nuclei and high DNA content …

Objective. To clarify the regulation of breast cancer cell‐derived exosomes on breast cancer
and the expression of the NUMB endocytic adaptor protein (NUMB) protein. Methods. The …