Coumarin heterocyclic derivatives: chemical synthesis and biological activity

FG Medina, JG Marrero, M Macías-Alonso… - Natural product …, 2015 - pubs.rsc.org
Coumarin heterocyclic derivatives: chemical synthesis and biological activity - Natural Product
Reports (RSC Publishing) DOI:10.1039/C4NP00162A Royal Society of Chemistry View PDF …

Multicomponent reactions in unconventional solvents: state of the art

Y Gu - Green Chemistry, 2012 - pubs.rsc.org
Simple and green synthetic procedures constitute an important goal in organic synthesis.
The combination of multicomponent reactions (MCRs) and unconventional solvents has …

Synthesis of α-aminophosphonates and related derivatives; The last decade of the Kabachnik–Fields reaction

PR Varga, G Keglevich - Molecules, 2021 - mdpi.com
The Kabachnik–Fields reaction, comprising the condensation of an amine, oxo compound
and a P-reagent (generally a> P (O) H species or trialkyl phosphite), still attracts interest due …

Mannich reaction: A versatile and convenient approach to bioactive skeletons

SG Subramaniapillai - Journal of Chemical Sciences, 2013 - Springer
This review gives an insight into the recent applications of Mannich reaction and its variants
in the construction of bioactive molecules. Emphasis is given to the Mannich reaction that …

New thiophene-derived α-aminophosphonic acids: Synthesis under microwave irradiations, antioxidant and antifungal activities, DFT investigations and SARS-CoV-2 …

H Tlidjane, N Chafai, S Chafaa, C Bensouici… - Journal of Molecular …, 2022 - Elsevier
Four new α-aminophosphonic acids containing thiophene ring have been synthesized using
simple, neat and catalyst-free conditions, more convenient and eco-friendly method under …

A focused review of synthetic applications of Lawesson's reagent in organic synthesis

H Khatoon, E Abdulmalek - Molecules, 2021 - mdpi.com
Lawesson's reagent (LR) is a well-known classic example of a compound with unique
construction and unusual chemical behavior, with a wide range of applications in synthetic …

Novel α-Aminophosphonates of imatinib Intermediate: Synthesis, anticancer Activity, human Abl tyrosine kinase Inhibition, ADME and toxicity prediction

S Aita, VN Badavath, M Gundluru, M Sudileti… - Bioorganic …, 2021 - Elsevier
An efficient method for the synthesis of a new class of α-aminophosphonates of imatinib
derivative has been developed in one-pot Kabachnik-Fields reaction of N-(5-amino-2-methyl …

α-Aminoazoles/azines: key reaction partners for multicomponent reactions

S Imtiaz, S Banoo - RSC advances, 2021 - pubs.rsc.org
Aromatic α-aminoazaheterocycles are the focus of significant investigations and exploration
by researchers owing to their key role in diverse biological and physiological processes. The …

Theoretical exploration on structures, bonding aspects and molecular docking of α-aminophosphonate ligated copper complexes against SARS-CoV-2 proteases

O Yadav, M Kumar, H Mittal, K Yadav… - Frontiers in …, 2022 - frontiersin.org
Recent years have witnessed a growing interest in the biological activity of metal complexes
of α-aminophosphonates. Here for the first time, a detailed DFT study on five α …

Diversity-oriented synthesis of α-aminophosphonates: A new class of potential anticancer agents

AK Bhattacharya, DS Raut, KC Rana, IK Polanki… - European Journal of …, 2013 - Elsevier
A small library of structurally diverse α-aminophosphonates has been synthesized by
reacting alkyl/aryl aldehydes, alkyl/aryl amines and alkyl/aryl phosphites in one-pot …