COVID-19 and diabetes mellitus: how one pandemic worsens the other
In light of the most challenging public health crisis of modern history, COVID-19 mortality
continues to rise at an alarming rate. Patients with co-morbidities such as hypertension …
continues to rise at an alarming rate. Patients with co-morbidities such as hypertension …
The mechanistic target of rapamycin (mTOR): novel considerations as an antiviral treatment
K Maiese - Current Neurovascular Research, 2020 - ingentaconnect.com
Multiple viral pathogens can pose a significant health risk to individuals. As a recent
example, the β-coronavirus family virion, SARS-CoV-2, has quickly evolved as a pandemic …
example, the β-coronavirus family virion, SARS-CoV-2, has quickly evolved as a pandemic …
Cognitive impairment and dementia: gaining insight through circadian clock gene pathways
K Maiese - Biomolecules, 2021 - mdpi.com
Neurodegenerative disorders affect fifteen percent of the world's population and pose a
significant financial burden to all nations. Cognitive impairment is the seventh leading cause …
significant financial burden to all nations. Cognitive impairment is the seventh leading cause …
[HTML][HTML] Neurodegeneration, memory loss, and dementia: the impact of biological clocks and circadian rhythm
K Maiese - Frontiers in bioscience (Landmark edition), 2021 - ncbi.nlm.nih.gov
Methods and results: Novel work with biological clock genes that oversee circadian rhythm
may meet this critical need by focusing upon the pathways of the mechanistic target of …
may meet this critical need by focusing upon the pathways of the mechanistic target of …
[HTML][HTML] Nicotinamide as a foundation for treating neurodegenerative disease and metabolic disorders
K Maiese - Current neurovascular research, 2021 - ncbi.nlm.nih.gov
Neurodegenerative disorders impact more than one billion individuals worldwide and are
intimately tied to metabolic disease that can affect another nine hundred individuals …
intimately tied to metabolic disease that can affect another nine hundred individuals …
Therapeutic potential of exploiting autophagy cascade against coronavirus infection
Since its emergence in December 2019 in Wuhan, China, severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) created a worldwide pandemic of coronavirus …
syndrome coronavirus 2 (SARS-CoV-2) created a worldwide pandemic of coronavirus …
Nicotinamide: oversight of metabolic dysfunction through sirt1, mtor, and clock genes
K Maiese - Current neurovascular research, 2020 - ingentaconnect.com
Metabolic disorders that include diabetes mellitus present significant challenges for
maintaining the welfare of the global population. Metabolic diseases impact all systems of …
maintaining the welfare of the global population. Metabolic diseases impact all systems of …
Mechanistic target of rapamycin signaling activation antagonizes autophagy to facilitate Zika virus replication
Zika virus (ZIKV), a mosquito-transmitted flavivirus, is linked to microcephaly and other
neurological defects in neonates and Guillain-Barré syndrome in adults. The molecular …
neurological defects in neonates and Guillain-Barré syndrome in adults. The molecular …
Progress in the development and application of transitional technology of surface-enhanced Raman spectroscopy
Surface-enhanced Raman scattering (SERS) is a molecularly specific spectroscopic
technique that has versatile applications in detection and analysis. To date, several studies …
technique that has versatile applications in detection and analysis. To date, several studies …
Initial hepatitis C virus infection of adult hepatocytes triggers a temporally structured transcriptional program containing diverse pro-and antiviral elements
Transcriptional profiling provides global snapshots of virus-mediated cellular
reprogramming, which can simultaneously encompass pro-and antiviral components. To …
reprogramming, which can simultaneously encompass pro-and antiviral components. To …