Microbial oils as food additives: recent approaches for improving microbial oil production and its polyunsaturated fatty acid content

S Bellou, IE Triantaphyllidou, D Aggeli… - Current opinion in …, 2016 - Elsevier
Highlights•Oleaginous fungi and microalgae are suitable sources of PUFAs.•Genetic
engineering for improving oil accumulation and fatty acid composition.•Overexpression of …

Advancing oleaginous microorganisms to produce lipid via metabolic engineering technology

MH Liang, JG Jiang - Progress in lipid research, 2013 - Elsevier
With the depletion of global petroleum and its increasing price, biodiesel has been
becoming one of the most promising biofuels for global fuels market. Researchers exploit …

Harnessing Yarrowia lipolytica lipogenesis to create a platform for lipid and biofuel production

J Blazeck, A Hill, L Liu, R Knight, J Miller, A Pan… - Nature …, 2014 - nature.com
Economic feasibility of biosynthetic fuel and chemical production hinges upon harnessing
metabolism to achieve high titre and yield. Here we report a thorough genotypic and …

Critical steps in carbon metabolism affecting lipid accumulation and their regulation in oleaginous microorganisms

M Dourou, D Aggeli, S Papanikolaou… - Applied Microbiology and …, 2018 - Springer
Oleaginous microorganisms are able to convert numerous agro-industrial and municipal
wastes into storage lipids (single cell oil (SCO)) and are therefore considered as potential …

Engineering acetyl-CoA metabolic shortcut for eco-friendly production of polyketides triacetic acid lactone in Yarrowia lipolytica

H Liu, M Marsafari, F Wang, L Deng, P Xu - Metabolic Engineering, 2019 - Elsevier
Acetyl-CoA is the central metabolic node connecting glycolysis, Krebs cycle and fatty acids
synthase. Plant-derived polyketides, are assembled from acetyl-CoA and malonyl-CoA …

The dilemma for lipid productivity in green microalgae: importance of substrate provision in improving oil yield without sacrificing growth

KWM Tan, YK Lee - Biotechnology for biofuels, 2016 - Springer
Rising oil prices and concerns over climate change have resulted in more emphasis on
research into renewable biofuels from microalgae. Unlike plants, green microalgae have …

Lipid metabolism research in oleaginous fungus Mortierella alpina: Current progress and future prospects

L Chang, H Lu, H Chen, X Tang, J Zhao, H Zhang… - Biotechnology …, 2022 - Elsevier
The oleaginous fungus Mortierella alpina has distinct advantages in long-chain PUFAs
production, and it is the only source for dietary arachidonic acid (ARA) certificated by FDA …

Current progress in lipid-based biofuels: Feedstocks and production technologies

J Wang, SD Singer, BA Souto, J Asomaning… - Bioresource …, 2022 - Elsevier
The expanding use of fossil fuels has caused concern in terms of both energy security and
environmental issues. Therefore, attempts have been made worldwide to promote the …

Accumulation of high-value lipids in single-cell microorganisms: a mechanistic approach and future perspectives

LA Garay, KL Boundy-Mills… - Journal of agricultural and …, 2014 - ACS Publications
In recent years attention has been focused on the utilization of microorganisms as
alternatives for industrial and nutritional applications. Considerable research has been …

Comparative lipid production by oleaginous yeasts in hydrolyzates of lignocellulosic biomass and process strategy for high titers

PJ Slininger, BS Dien, CP Kurtzman… - Biotechnology and …, 2016 - Wiley Online Library
Oleaginous yeasts can convert sugars to lipids with fatty acid profiles similar to those of
vegetable oils, making them attractive for production of biodiesel. Lignocellulosic biomass is …