DNA tetrahedron nanostructures for biological applications: biosensors and drug delivery
With the rapid development of DNA nanotechnology, various DNA nanostructures with
different shapes and sizes have been self-assembled using “bottom-up” fabrication …
different shapes and sizes have been self-assembled using “bottom-up” fabrication …
Biological and medical applications of calcium phosphate nanoparticles
V Sokolova, M Epple - Chemistry–A European Journal, 2021 - Wiley Online Library
Calcium phosphate nanoparticles have a high biocompatibility and biodegradability due to
their chemical similarity to human hard tissue, for example, bone and teeth. They can be …
their chemical similarity to human hard tissue, for example, bone and teeth. They can be …
Aptamer-based targeted delivery systems for cancer treatment using DNA origami and DNA nanostructures
A Jabbari, E Sameiyan, E Yaghoobi… - International Journal of …, 2023 - Elsevier
Due to the limitations of conventional cancer treatment methods, nanomedicine has
appeared as a promising alternative, allowing improved drug targeting and decreased drug …
appeared as a promising alternative, allowing improved drug targeting and decreased drug …
Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage
We demonstrate temperature-controlled encapsulation and release of the enzyme
horseradish peroxidase using a preassembled and covalently closed three-dimensional …
horseradish peroxidase using a preassembled and covalently closed three-dimensional …
Receptor-mediated entry of pristine octahedral DNA nanocages in mammalian cells
DNA offers excellent programming properties for the generation of nanometer-scaled
polyhedral structures with a broad variety of potential applications. Translation to biomedical …
polyhedral structures with a broad variety of potential applications. Translation to biomedical …
AS1411 aptamer linked to DNA nanostructures diverts its traffic inside cancer cells and improves its therapeutic efficacy
The nucleolin-binding G-quadruplex AS1411 aptamer has been widely used for cancer
therapy and diagnosis and linked to nanoparticles for its selective targeting activity. We …
therapy and diagnosis and linked to nanoparticles for its selective targeting activity. We …
Selective targeting and degradation of doxorubicin-loaded folate-functionalized DNA nanocages
S Raniolo, G Vindigni, A Ottaviani, V Unida… - … , Biology and Medicine, 2018 - Elsevier
Selective targeting is a crucial property of nanocarriers used for drug delivery in cancer
therapy. We generated biotinylated octahedral DNA nanocages functionalized with folic acid …
therapy. We generated biotinylated octahedral DNA nanocages functionalized with folic acid …
Shape and interhelical spacing of DNA origami nanostructures studied by small-angle X-ray scattering
Scaffolded DNA origami nanostructures enable the self-assembly of arbitrarily shaped
objects with unprecedented accuracy. Yet, varying physiological conditions are prone to …
objects with unprecedented accuracy. Yet, varying physiological conditions are prone to …
Peptide-conjugated ultrasmall gold nanoparticles (2 nm) for selective protein targeting
Ultrasmall gold nanoparticles with a metallic core diameter of 2 nm were surface-conjugated
with peptides that selectively target epitopes on the surface of the WW domain of the model …
with peptides that selectively target epitopes on the surface of the WW domain of the model …