DNA origami nano-mechanics

J Ji, D Karna, H Mao - Chemical Society Reviews, 2021 - pubs.rsc.org
Invention of DNA origami has transformed the fabrication and application of biological
nanomaterials. In this review, we discuss DNA origami nanoassemblies according to their …

DNA tetrahedron nanostructures for biological applications: biosensors and drug delivery

N Xie, S Liu, X Yang, X He, J Huang, K Wang - Analyst, 2017 - pubs.rsc.org
With the rapid development of DNA nanotechnology, various DNA nanostructures with
different shapes and sizes have been self-assembled using “bottom-up” fabrication …

Biological and medical applications of calcium phosphate nanoparticles

V Sokolova, M Epple - Chemistry–A European Journal, 2021 - Wiley Online Library
Calcium phosphate nanoparticles have a high biocompatibility and biodegradability due to
their chemical similarity to human hard tissue, for example, bone and teeth. They can be …

Aptamer-based targeted delivery systems for cancer treatment using DNA origami and DNA nanostructures

A Jabbari, E Sameiyan, E Yaghoobi… - International Journal of …, 2023 - Elsevier
Due to the limitations of conventional cancer treatment methods, nanomedicine has
appeared as a promising alternative, allowing improved drug targeting and decreased drug …

Temperature-controlled encapsulation and release of an active enzyme in the cavity of a self-assembled DNA nanocage

S Juul, F Iacovelli, M Falconi, SL Kragh… - ACS …, 2013 - ACS Publications
We demonstrate temperature-controlled encapsulation and release of the enzyme
horseradish peroxidase using a preassembled and covalently closed three-dimensional …

Receptor-mediated entry of pristine octahedral DNA nanocages in mammalian cells

G Vindigni, S Raniolo, A Ottaviani, M Falconi… - ACS …, 2016 - ACS Publications
DNA offers excellent programming properties for the generation of nanometer-scaled
polyhedral structures with a broad variety of potential applications. Translation to biomedical …

AS1411 aptamer linked to DNA nanostructures diverts its traffic inside cancer cells and improves its therapeutic efficacy

G Vindigni, S Raniolo, F Iacovelli, V Unida, C Stolfi… - Pharmaceutics, 2021 - mdpi.com
The nucleolin-binding G-quadruplex AS1411 aptamer has been widely used for cancer
therapy and diagnosis and linked to nanoparticles for its selective targeting activity. We …

Selective targeting and degradation of doxorubicin-loaded folate-functionalized DNA nanocages

S Raniolo, G Vindigni, A Ottaviani, V Unida… - … , Biology and Medicine, 2018 - Elsevier
Selective targeting is a crucial property of nanocarriers used for drug delivery in cancer
therapy. We generated biotinylated octahedral DNA nanocages functionalized with folic acid …

Shape and interhelical spacing of DNA origami nanostructures studied by small-angle X-ray scattering

S Fischer, C Hartl, K Frank, JO Rädler, T Liedl… - Nano …, 2016 - ACS Publications
Scaffolded DNA origami nanostructures enable the self-assembly of arbitrarily shaped
objects with unprecedented accuracy. Yet, varying physiological conditions are prone to …

Peptide-conjugated ultrasmall gold nanoparticles (2 nm) for selective protein targeting

T Ruks, K Loza, M Heggen, O Prymak… - ACS Applied Bio …, 2021 - ACS Publications
Ultrasmall gold nanoparticles with a metallic core diameter of 2 nm were surface-conjugated
with peptides that selectively target epitopes on the surface of the WW domain of the model …