Arginine methylation is an influential post-translational modification occurring on histones,
RNA binding proteins, and many other cellular proteins, affecting their function by altering …

Osteoporosis is a systemic degenerative bone disease characterized by low bone mass and
damage to bone microarchitecture, which increases bone fragility and susceptibility to …

Osteogenic differentiation of mesenchymal cells is controlled by epigenetic enzymes that
regulate post-translational modifications of histones. Compared to acetyl or …

Bone formation and homeostasis are controlled by environmental factors and endocrine
regulatory cues that initiate intracellular signaling pathways capable of modulating gene …

Airway wall remodeling, a main pathology of asthma was linked to vitamin-D deficiency and
protein arginine methyltransferase-1 (PRMT1) expression in sub-epithelial cell layers …

Mesenchymal stem cells (MSCs) gain an increasing focus in the field of regenerative
medicine due to their differentiation abilities into chondrocytes, adipocytes, and osteoblastic …

1, 25-Dihydroxyvitamin D3 (1, 25 (OH) 2D3), the hormonally active form of vitamin D,
activates the nuclear vitamin D receptor (VDR) to mediate the transcription of target genes …

Oral squamous cell carcinoma (OSCC) is a malignancy all over the world. WD repeat
domain 5 (WDR5) is involved in cancer progression. In addition, it was reported that WDR5 …

In patients on maintenance hemodialysis (MHD), vascular calcification (VC) is an
independent predictor of cardiovascular disease (CVD), which is the primary cause of death …

Epigenetic control is critical for the regulation of gene transcription in mammalian cells.
Among the most important epigenetic mechanisms are those associated with …