Brain imaging technology has allowed researchers to conduct rigorous studies of the
dynamic course of alcoholism through periods of drinking, sobriety, and relapse and to gain …

Numerous lines of inquiry implicate connectivity as a central abnormality in schizophrenia.
Myelination and factors that affect myelination, such as the function of oligodendroglia, are …

Neuropathological and brain imaging studies suggest that schizophrenia may result from
neurodevelopmental defects. Cytoarchitectural studies indicate cellular abnormalities …

Gyrification is the process by which the brain undergoes changes in surface morphology to
create sulcal and gyral regions. The period of greatest development of brain gyrification is …

Background In patients with schizophrenia, deficient generation of mismatch negativity
(MMN)—an event-related potential (ERP) indexing auditory sensory (" echoic") memory …

Adolescence to early adulthood is a period of dramatic transformation in the healthy human
brain. However, the relationship between the concurrent structural and functional changes …

The history of psychiatric research is filled with widely accepted etiologic and
pathophysiologic theories that eventually were proven wrong. The prevailing …

Schizophrenia unfolds during the late period of brain maturation, while myelination is still
continuing. In the present study, we used MRI and T2 relaxation analysis to measure the …

Background We sought to determine whether the brain dysmorphology previously observed
cross-sectionally in people with schizophrenia progresses over time and whether such …

Background Current investigations suggest that brain white matter may be qualitatively
altered in schizophrenia even in the face of normal white matter volume. Diffusion tensor …