Luminescence imaging is a powerful and versatile technique for investigating cell
physiology and pathology in living systems, making significant contributions to life science …

Hypoxia development in tumor is closely associated with its increased aggressiveness and
strong resistance to therapy, leading to the poor prognosis in several cancer types …

Porphyrins and related macrocycles have been intensively exploited as sensing materials in
chemical sensors, since in these devices they mimic most of their biological functions, such …

A glucose-responsive “closed-loop” insulin delivery system mimicking the function of
pancreatic cells has tremendous potential to improve quality of life and health in diabetics …

We review the current state of optical methods for sensing oxygen. These have become
powerful alternatives to electrochemical detection and in the process of replacing the Clark …

Optical and photonic technologies play an important role in human progress. The bending of
light to our will has not only enabled our biological self-discovery, but has also allowed us to …

A light-activated hypoxia-responsive conjugated polymer-based nanocarrier is developed
for efficiently producing singlet oxygen (1O2) and inducing hypoxia to promote release of its …

The extensive oxygen gradient between the air we breathe (Po2~ 21 kPa) and its ultimate
distribution within mitochondria (as low as~ 0.5–1 kPa) is testament to the efforts expended …

Recent developments in the area of biological detection by optical sensing of molecular
oxygen (O2) are reviewed, with particular emphasis on the quenched-phosphorescence O2 …

Porphyrins and related families of molecules are important organic modules as has been
reflected in the award of the Nobel Prizes in Chemistry in 1915, 1930, 1961, 1962, 1965 …