Cancer treatments which include conventional chemotherapy have not proven very
successful in curing human malignancies. The failures of these treatment modalities include …

In this review, we present a timeline that shows the origin of mixed chelate copper (II)
complexes, registered as Mark Title Casiopeínas®, as the first copper (II) compounds …

The interpretation of in vitro cytotoxicity data of Cu (II)-1, 10-phenanthroline (phen)
complexes normally does not take into account the speciation that complexes undergo in …

Due to the emergence of multi-drug resistant strains, development of novel antibiotics has
become a critical issue. One promising approach is the use of transition metals, since they …

Bis (pyrazol-1-yl)-and bis (3, 5-dimethylpyrazol-1-yl)-acetates were conjugated with the 2-
hydroxyethylester and 2-aminoethylamide derivatives of the antineoplastic drug lonidamine …

Recent evidence has shown that nanoparticles that have been used to improve or create
new functional properties for common products may pose potential risks to human health …

Background Silica nanoparticles (nanoSiO 2) are promising systems that can deliver
biologically active compounds to tissues such as the heart in a controllable manner …

Pulmonary arterial hypertension (PAH) is characterized by pulmonary vessel remodeling;
however, its severity and impact on survival depend on right ventricular (RV) failure …

In the present study, four new mixed-ligand copper (II) complexes with 5-benzyltetrazole
(HL) and polypyridine ligands (phen–1, 10-phenanthroline, dmphen–4, 7-dimethyl-1, 10 …

Mixed-ligand copper (II) complexes based on 1, 10-phenanthroline and related compounds
are of interest to scientists due to their promising anticancer properties. In this study, four …