The promising role of new molecular biomarkers in prostate cancer: From coding and non-coding genes to artificial intelligence approaches

AP Alarcón-Zendejas, A Scavuzzo… - Prostate cancer and …, 2022 - nature.com
Background Risk stratification or progression in prostate cancer is performed with the
support of clinical-pathological data such as the sum of the Gleason score and serum levels …

Human endogenous retrovirus K (HML-2) in health and disease

B Xue, LA Sechi, DJ Kelvin - Frontiers in microbiology, 2020 - frontiersin.org
Human endogenous retroviruses (HERVs) are derived from exogenous retrovirus infections
in the evolution of primates and account for about 8% of the human genome. They were …

An overview of cancer health disparities: new approaches and insights and why they matter

TZ Minas, M Kiely, A Ajao, S Ambs - Carcinogenesis, 2021 - academic.oup.com
Cancer health disparities remain stubbornly entrenched in the US health care system. The
Affordable Care Act was legislation to target these disparities in health outcomes. Expanded …

Human endogenous retrovirus K in cancer: a potential biomarker and immunotherapeutic target

G Curty, JL Marston, M de Mulder Rougvie, FE Leal… - Viruses, 2020 - mdpi.com
In diseases where epigenetic mechanisms are changed, such as cancer, many genes show
altered gene expression and inhibited genes become activated. Human endogenous …

[HTML][HTML] Human endogenous retroviruses in development and disease

J Mao, Q Zhang, YS Cong - Computational and Structural Biotechnology …, 2021 - Elsevier
Human endogenous retroviruses (HERVs) represent∼ 8% of human genome, deriving from
exogenous retroviral infections of germ line cells occurred millions of years ago and being …

HERVs new role in cancer: from accused perpetrators to cheerful protectors

N Bannert, H Hofmann, A Block, O Hohn - Frontiers in microbiology, 2018 - frontiersin.org
Initial indications that retroviruses are connected to neoplastic transformation were seen
more than a century ago. This concept has also been tested for endogenized retroviruses …

Human endogenous retrovirus K and cancer: Innocent bystander or tumorigenic accomplice?

RF Downey, FJ Sullivan… - … Journal of Cancer, 2015 - Wiley Online Library
Harbored as relics of ancient germline infections, human endogenous retroviruses (HERVs)
now constitute up to 8% of our genome. A proportion of this sequence has been co‐opted for …

[HTML][HTML] Glycolysis gene expression profilings screen for prognostic risk signature of hepatocellular carcinoma

L Jiang, L Zhao, J Bi, Q Guan, A Qi, Q Wei, M He… - Aging (Albany …, 2019 - ncbi.nlm.nih.gov
Metabolic changes are the markers of cancer and have attracted wide attention in recent
years. One of the main metabolic features of tumor cells is the high level of glycolysis, even if …

Ancient adversary–HERV-K (HML-2) in cancer

E Dervan, DD Bhattacharyya, JD McAuliffe… - Frontiers in …, 2021 - frontiersin.org
Human endogenous retroviruses (HERV), ancient integrations of exogenous viruses, make
up 8% of our genome. Long thought of as mere vestigial genetic elements, evidence is now …

[HTML][HTML] Human endogenous retroviruses as gene expression regulators: insights from animal models into human diseases

S Durnaoglu, SK Lee, J Ahnn - Molecules and cells, 2021 - Elsevier
The human genome contains many retroviral elements called human endogenous
retroviruses (HERVs), resulting from the integration of retroviruses throughout evolution …