Glioblastoma therapy: past, present and future

E Obrador, P Moreno-Murciano… - International journal of …, 2024 - mdpi.com
Glioblastoma (GB) stands out as the most prevalent and lethal form of brain cancer.
Although great efforts have been made by clinicians and researchers, no significant …

Therapeutic targeting of glioblastoma and the interactions with its microenvironment

V Genoud, B Kinnersley, NF Brown, D Ottaviani… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma (GBM) is the most aggressive brain tumour. Patients with
GBM have a dismal survival and there is a distinct lack of curative treatments. We are …

Bridging the age gap: a review of molecularly informed treatments for glioma in adolescents and young adults

A Weiser, A Sanchez Bergman, C Machaalani… - Frontiers in …, 2023 - frontiersin.org
Gliomas are the most common primary central nervous system (CNS) tumors and a major
cause of cancer-related mortality in children (age< 15 years), adolescents and young adults …

Advancements and challenges: immunotherapy therapy in high-grade glioma-a meta-analysis of randomized clinical trials

LB Palavani, LP Mitre, R Camerotte… - Journal of Neuro …, 2024 - Springer
Background High-grade gliomas (HGG) are the most aggressive primary brain tumors with
poor prognoses despite conventional treatments. Immunotherapy has emerged as a …

Treatment advances in high-grade gliomas

X Chen, Y Cui, L Zou - Frontiers in Oncology, 2024 - frontiersin.org
High-grade gliomas (HGG) pose significant challenges in modern tumour therapy due to the
distinct biological properties and limitations of the blood-brain barrier. This review discusses …