Neutralizing Effects of Small Molecule Inhibitors and Metal Chelators on Coagulopathic Viperinae Snake Venom Toxins
C Xie, LO Albulescu, MA Bittenbinder, GW Somsen… - Biomedicines, 2020 - mdpi.com
Animal-derived antivenoms are the only specific therapies currently available for the
treatment of snake envenoming, but these products have a number of limitations associated …
treatment of snake envenoming, but these products have a number of limitations associated …
The procoagulant snake venom serine protease potentially having a dual, blood coagulation factor V and X-activating activity
A procoagulant snake venom serine protease was isolated from the venom of the nose-
horned viper (Vipera ammodytes ammodytes). This 34 kDa glycoprotein, termed Vaa SP-VX …
horned viper (Vipera ammodytes ammodytes). This 34 kDa glycoprotein, termed Vaa SP-VX …
Unraveling the Reaction Mechanism of Russell's Viper Venom Factor X Activator: A Paradigm for the Reactivity of Zinc Metalloproteinases?
J Castro-Amorim, A Oliveira… - Journal of Chemical …, 2023 - ACS Publications
Snake venom metalloproteinases (SVMPs) are important drug targets against snakebite
envenoming, the neglected tropical disease with the highest mortality worldwide. Here, we …
envenoming, the neglected tropical disease with the highest mortality worldwide. Here, we …
Comparative gender peptidomics of Bothrops atrox venoms: are there differences between them?
A Simizo, ES Kitano, SS Sant'Anna… - Journal of Venomous …, 2020 - SciELO Brasil
Background: Bothrops atrox is known to be the pit viper responsible for most snakebites and
human fatalities in the Amazon region. It can be found in a wide geographical area including …
human fatalities in the Amazon region. It can be found in a wide geographical area including …
Intraspecific Differences in the Venom of Crotalus durissus cumanensis from Colombia
Biochemical and biological differences in the venom of Crotalus durissus cumanensis from
three ecoregions of Colombia were evaluated. Rattlesnakes were collected from the …
three ecoregions of Colombia were evaluated. Rattlesnakes were collected from the …
Immunorecognition and Neutralization of Crotalus durissus cumanensis Venom by a Commercial Antivenom Produced in Colombia
In Colombia, on average 2.9% of the nearly 5600 snakebite events that occur annually
involve the rattlesnake Crotalus durissus cumanensis. The envenomation by this snake is …
involve the rattlesnake Crotalus durissus cumanensis. The envenomation by this snake is …
Qualitative Profiling of Venom Toxins in the Venoms of Several Bothrops Species Using High-Throughput Venomics and Coagulation Bioassaying
DJC Weekers, LL Alonso, AX Verstegen, J Slagboom… - Toxins, 2024 - mdpi.com
Envenoming resulting from snakebites is recognized as a priority neglected tropical disease
by The World Health Organization. The Bothrops genus, consisting of different pitviper …
by The World Health Organization. The Bothrops genus, consisting of different pitviper …
[HTML][HTML] Analysis and Identification of Putative Novel Peptides Purified from Iranian Endemic Echis Carinatus Sochureki Snake Venom by MALDI-TOF Mass …
NN Nasrabadi, H Vatanpour, NM Dounighi… - Archives of Razi …, 2023 - ncbi.nlm.nih.gov
Abstract The Iranian Echis Carinatus (IEC) venom is an exclusive natural source of bio-
substances for a wide range of purposes in the blood coagulation cascade. The present …
substances for a wide range of purposes in the blood coagulation cascade. The present …