How will we view schizophrenia in 2030? Schizophrenia today is a chronic, frequently
disabling mental disorder that affects about one per cent of the world's population. After a …

Schizophrenia is a severe mental illness that affects almost 1% of the population worldwide.
Even though the etiology of schizophrenia is uncertain, it is believed to be a …

Background Twin studies have provided evidence that both genetic and environmental
factors contribute to schizophrenia (SZ) risk. Heritability estimates of SZ in twin samples …

We conducted a combined genome-wide association study (GWAS) of 7,481 individuals
with bipolar disorder (cases) and 9,250 controls as part of the Psychiatric GWAS …

Schizophrenia is a heritable complex phenotype associated with a background risk
involving multiple common genetic variants of small effect and a multitude of environmental …

Background We conducted a systematic review of incidence rates in England over a sixty-
year period to determine the extent to which rates varied along accepted (age, sex) and less …

Schizophrenia is a neurodevelopmental disorder whose clinical features include
impairments in perception, cognition and motivation. These impairments reflect alterations in …

Context There are many published twin studies of schizophrenia. Although these studies
have been reviewed previously, to our knowledge, no review has provided quantitative …

Background Twin studies of bipolar affective disorder (BPD) have either been small or have
not used explicit diagnostic criteria. There has been little use of genetic model fitting and no …

There is abundant evidence, some of it reviewed in this paper, that personality traits are
substantially influenced by the genes. Much remains to be understood about how and why …