[HTML][HTML] miRNA-based biomarkers, therapies, and resistance in Cancer
B He, Z Zhao, Q Cai, Y Zhang, P Zhang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Abstract MicroRNAs (miRNAs), small non-coding RNAs (ncRNAs) of about 22 nucleotides in
size, play important roles in gene regulation, and their dysregulation is implicated in human …
size, play important roles in gene regulation, and their dysregulation is implicated in human …
Regulation of gene expression by cis-acting long non-coding RNAs
N Gil, I Ulitsky - Nature Reviews Genetics, 2020 - nature.com
Long non-coding RNAs (lncRNAs) are diverse transcription products emanating from
thousands of loci in mammalian genomes. Cis-acting lncRNAs, which constitute a …
thousands of loci in mammalian genomes. Cis-acting lncRNAs, which constitute a …
[HTML][HTML] The non-canonical aspects of microRNAs: many roads to gene regulation
CJ Stavast, SJ Erkeland - Cells, 2019 - mdpi.com
MicroRNAs (miRNAs) are critical regulators of gene expression. As miRNAs are frequently
deregulated in many human diseases, including cancer and immunological disorders, it is …
deregulated in many human diseases, including cancer and immunological disorders, it is …
[HTML][HTML] Global positioning system: understanding long noncoding RNAs through subcellular localization
J Carlevaro-Fita, R Johnson - Molecular cell, 2019 - cell.com
The localization of long noncoding RNAs (lncRNAs) within the cell is the primary
determinant of their molecular functions. LncRNAs are often thought of as chromatin …
determinant of their molecular functions. LncRNAs are often thought of as chromatin …
Non-canonical features of microRNAs: paradigms emerging from cardiovascular disease
D Santovito, C Weber - Nature Reviews Cardiology, 2022 - nature.com
Research showing that microRNAs (miRNAs) are versatile regulators of gene expression
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …
has instigated tremendous interest in cardiovascular research. The overwhelming majority of …
Dicer dependent tRNA derived small RNAs promote nascent RNA silencing
A Di Fazio, M Schlackow, SK Pong… - Nucleic Acids …, 2022 - academic.oup.com
In mammalian cells, small non-coding RNAs (sncRNAs) negatively regulate gene
expression in a pathway known as RNA interference (RNAi). RNAi can be categorized into …
expression in a pathway known as RNA interference (RNAi). RNAi can be categorized into …
[HTML][HTML] Argonaute proteins: from structure to function in development and pathological cell fate determination
M Müller, F Fazi, C Ciaudo - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
The highly conserved Argonaute protein family members play a central role in the regulation
of gene expression networks, orchestrating the establishment and the maintenance of cell …
of gene expression networks, orchestrating the establishment and the maintenance of cell …
Nuclear localization of Argonaute 2 is affected by cell density and may relieve repression by microRNAs
KC Johnson, A Kilikevicius, C Hofman, J Hu… - Nucleic acids …, 2024 - academic.oup.com
Argonaute protein is associated with post-transcriptional control of cytoplasmic gene
expression through miRNA-induced silencing complexes (miRISC). Specific cellular and …
expression through miRNA-induced silencing complexes (miRISC). Specific cellular and …
[HTML][HTML] Long noncoding RNA TRPM2-AS acts as a microRNA sponge of miR-612 to promote gastric cancer progression and radioresistance
J Xiao, L Lin, D Luo, L Shi, W Chen, H Fan, Z Li, X Ma… - Oncogenesis, 2020 - nature.com
Long noncoding RNAs (lncRNAs) are emerging as important regulators of tumorigenesis
and are frequently dysregulated in cancers. Here, we identify a critical lncRNA TRPM2-AS …
and are frequently dysregulated in cancers. Here, we identify a critical lncRNA TRPM2-AS …