Heavy metals exposure and Alzheimer's disease: Underlying mechanisms and advancing therapeutic approaches

NA Althobaiti - Behavioural Brain Research, 2024 - Elsevier
Heavy metals such as lead, cadmium, mercury, and arsenic are prevalent in the
environment due to both natural and anthropogenic sources, leading to significant public …

Recent advances in carbon dots for electrochemical sensing and biosensing: a systematic review

L Wang, C Gu, L Wu, W Tan, Z Shang, Y Tian… - Microchemical Journal, 2024 - Elsevier
Carbon dots (CDs) are a class of emerging carbon-based nanomaterials with an average
particle size of less than 10 nm. CDs have received considerable attention due to their …

The diverse roles of reactive astrocytes in the pathogenesis of amyotrophic lateral sclerosis

K Yang, Y Liu, M Zhang - Brain Sciences, 2024 - mdpi.com
Astrocytes displaying reactive phenotypes are characterized by their ability to remodel
morphologically, molecularly, and functionally in response to pathological stimuli. This …

Uncovering the relationship between trace element exposure, cognitive function, and dietary inflammation index in elderly americans from the National Health and …

C Tang, M Shen, H Hong - BMC Public Health, 2024 - Springer
Background The consequences of trace element exposure on cognitive function in elderly
adults have been recognized as primarily attributed to the inflammatory response. It is …

[HTML][HTML] Morphological and metabolic changes in microglia exposed to cadmium: cues on neurotoxic mechanisms

F Bovio, E Perciballi, P Melchioretto, D Ferrari… - Environmental …, 2024 - Elsevier
Microglial cells play a key role in protecting the central nervous system from pathogens and
toxic compounds and are involved in the pathogenesis of different neurodegenerative …

Rlip76 in Ageing and Alzheimer's Disease: Focus on Oxidative Stress and Mitochondrial Mechanisms

M Bandaru, OF Sultana, MA Islam, A Rainier… - Ageing Research …, 2024 - Elsevier
Abstract RLIP76 (Rlip), a stress-responsive protein, plays a multifaceted role in cellular
function. This protein acts primarily as a glutathione-electrophile conjugate (GS-E) …

[HTML][HTML] Covalent organic framework-based materials for ion separation: A review

AR Bagheri, H Su, A Shokrollahi, A Samadi… - Chemical Engineering …, 2024 - Elsevier
Separation and purification of valuable ions from water is an area of interest to deal with
environmental pollution and energy crisis. Although various materials have been developed …

Angelica sinensis polysaccharides mitigate cadmium-induced apoptosis in layer chicken chondrocytes by inhibiting the JNK signaling pathway

X Tong, G Wang, X Zhao, J Zhou, P Wang, H Xia… - International Journal of …, 2024 - Elsevier
Cadmium (Cd), a toxic heavy metal pollutant, inflicts widespread damage on various organs
and tissues, including cartilage, where it induces chondrocyte apoptosis. Angelica sinensis …

[HTML][HTML] The role of exosome-shuttled miRNAs in heavy metal-induced peripheral tissues and neuroinflammation in Alzheimer's disease

Q Dong, H Fu, H Jiang - Biomedicine & Pharmacotherapy, 2024 - Elsevier
Heavy metal-induced neuroinflammation is a significant pathophysiologic mechanism in
Alzheimer's disease (AD). Microglia-mediated neuroinflammation plays a crucial role in the …

[HTML][HTML] Evidence for chromium crosses blood brain barrier from the hypothalamus in chromium mice model

J Ding, B Sun, Y Gao, J Zheng, C Liu, J Huang… - Ecotoxicology and …, 2024 - Elsevier
It has been shown that exposure to hexavalent Chromium, Cr (Ⅵ), via nasal cavity can have
neurotoxicological effects and induces behavioral impairment due to the fact that blood brain …