Hydrogel and nanomedicine‐based multimodal therapeutic strategies for spinal cord injury

P Yin, W Liang, B Han, Y Yang, D Sun, X Qu… - Small …, 2024 - Wiley Online Library
Spinal cord injury (SCI) is a severe neurodegenerative disease caused by mechanical and
biological factors, manifesting as a loss of motor and sensory functions. Inhibition of injury …

[HTML][HTML] Hydrogel scaffolds in the treatment of spinal cord injury: a review

M Cai, L Chen, T Wang, Y Liang, J Zhao… - Frontiers in …, 2023 - frontiersin.org
Spinal cord injury (SCI) is a disease of the central nervous system often caused by
accidents, and its prognosis is unsatisfactory, with long-term adverse effects on patients' …

UV Irradiation-Induced Cyclic-to-Linear Topological Changes of a Light/pH Dual-Sensitive Cyclic Copolymer for Enhanced Drug Delivery

H Liu, Z Guo, W Ma, S Li, D Wang, Z Zheng… - ACS Macro …, 2023 - ACS Publications
Cyclic polymers with cleavable backbones triggered by either external or internal stimuli can
realize simultaneous extracellular stability and intracellular destabilization of cyclic polymer …

Tail nerve electrical stimulation promoted the efficiency of transplanted spinal cord-like tissue as a neuronal relay to repair the motor function of rats with transected …

BQ Lai, RJ Wu, WT Han, YR Bai, JL Liu, HY Yu… - Biomaterials, 2023 - Elsevier
Following transected spinal cord injury (SCI), there is a critical need to restore nerve
conduction at the injury site and activate the silent neural circuits caudal to the injury to …

Harnessing the power of biological macromolecules in hydrogels for controlled drug release in the central nervous system: A review

S Ghosh, S Ghosh, H Sharma, R Bhaskar… - International Journal of …, 2023 - Elsevier
Hydrogels have immense potential in revolutionizing central nervous system (CNS) drug
delivery, improving outcomes for neurological disorders. They serve as promising tools for …

Polysaccharides as a promising platform for the treatment of spinal cord injury: A review

Y Yang, R Fan, H Li, H Chen, H Gong, G Guo - Carbohydrate Polymers, 2023 - Elsevier
Spinal cord injury is incurable and often results in irreversible damage to motor function and
autonomic sensory abilities. To enhance the effectiveness of therapeutic substances such as …

Hydrogel-based therapeutic strategies for spinal cord injury repair: Recent advances and future prospects

N Li, J He - International Journal of Biological Macromolecules, 2024 - Elsevier
Spinal cord injury (SCI) is a debilitating condition that can result in significant functional
impairment and loss of quality of life. There is a growing interest in developing new …

Role of epidural fat in the local milieu: what we know and what we don't

Z Liu, Y Wang, X Ma, L Zhang… - Connective Tissue …, 2024 - Taylor & Francis
Purpose Traditionally, the epidural fat (EF) is known as a physical buffer for the dural sac
against the force and a lubricant facilitating the relative motion of the latter on the osseous …

[HTML][HTML] Hydrogel-based treatments for spinal cord injuries

Z Jia, H Zeng, X Ye, M Dai, C Tang, L Liu - Heliyon, 2023 - cell.com
Spinal cord injury (SCI) is characterized by damage resulting in dysfunction of the spinal
cord. Hydrogels are common biomaterials that play an important role in the treatment of SCI …

QML-FFSD: A Novel Approach for Early Detection of SCDs through Feature Fusion of Antibiotics Composition and Symptoms Data using Quantum ML

A Sinha, V Kumar, V Sharma… - 2023 IEEE IAS Global …, 2023 - ieeexplore.ieee.org
Spinal cord disorders (SCDs) are a significant cause of morbidity worldwide, and early
detection of SCDs is crucial for improving patient outcomes. In the existing clinical systems …