Development of nanozymes for promising alleviation of COVID-19-associated arthritis

D Li, B Zhao, P Zhuang, X Mei - Biomaterials Science, 2023 - pubs.rsc.org
The COVID-19 pandemic caused by SARS-CoV-2 has been identified as a culprit in the
development of a variety of disorders, including arthritis. Although the emergence of arthritis …

[HTML][HTML] β Cell and autophagy: what do we know?

HR Mohammadi-Motlagh, M Sadeghalvad, N Yavari… - Biomolecules, 2023 - mdpi.com
Pancreatic β cells are central to glycemic regulation through insulin production. Studies
show autophagy as an essential process in β cell function and fate. Autophagy is a catabolic …

Cobalt induces neurodegenerative damages through impairing autophagic flux by activating hypoxia-inducible factor-1α triggered ROS overproduction

J Tang, Y Li, X Liu, G Yu, F Zheng, Z Guo… - Science of The Total …, 2023 - Elsevier
Cobalt is an environmental toxicant, and excessive bodily exposure can damage the
nervous system. Particularly, our previous study reported that low-dose cobalt (significantly …

[HTML][HTML] The peroxisome-autophagy redox connection: a double-edged sword?

H Li, C Lismont, I Revenco, MAF Hussein… - Frontiers in Cell and …, 2021 - frontiersin.org
Peroxisomes harbor numerous enzymes that can produce or degrade hydrogen peroxide
(H2O2). Depending on its local concentration and environment, this oxidant can function as …

[HTML][HTML] Identification of brain-enriched proteins in CSF as biomarkers of relapsing remitting multiple sclerosis

LI Wurtz, E Knyazhanskaya, D Sohaei, I Prassas… - Clinical Proteomics, 2024 - Springer
Background Multiple sclerosis (MS) is a clinically and biologically heterogenous disease
with currently unpredictable progression and relapse. After the development and success of …

[HTML][HTML] Management of oxidative stress for cell therapy through combinational approaches of stem cells, antioxidants, and photobiomodulation

R Asgari, YZ Mehran, HM Weber, M Weber… - European Journal of …, 2024 - Elsevier
Over the recent decades, stem cell-based therapies have been considered as a beneficial
approach for the treatment of various diseases. In these types of therapies, the stem cells …

Reduced expression of mitochondrial fumarate hydratase in progressive multiple sclerosis contributes to impaired in vitro mesenchymal stromal cell-mediated …

P Sarkar, J Redondo, K Hares, S Bailey… - Multiple Sclerosis …, 2022 - journals.sagepub.com
Background: Cell-based therapies for multiple sclerosis (MS), including those employing
autologous bone marrow-derived mesenchymal stromal cells (MSC) are being examined in …

Liensinine sensitizes colorectal cancer cells to oxaliplatin by targeting HIF-1α to inhibit autophagy

Z Feng, S Zhang, Q Han, T Chu, H Wang, L Yu… - Phytomedicine, 2024 - Elsevier
Background Oxaliplatin is the most common chemotherapeutic agent for patients with
colorectal cancer. However, its anti-cancer efficacy is restricted by drug resistance occurring …

Increased formation of neutrophil extracellular traps induced by autophagy and identification of autophagy‐related biomarkers in systemic lupus erythematosus

M Li, L Weng, D Yu, G Yang… - Experimental Dermatology, 2024 - Wiley Online Library
Abnormal death of neutrophils and the subsequent ineffective clearance of cell fragments
result in production of autoantigens that can lead to systemic lupus erythematosus (SLE) …