Ageing, cellular senescence and neurodegenerative disease
M Kritsilis, S V. Rizou, PN Koutsoudaki… - International journal of …, 2018 - mdpi.com
Ageing is a major risk factor for developing many neurodegenerative diseases. Cellular
senescence is a homeostatic biological process that has a key role in driving ageing. There …
senescence is a homeostatic biological process that has a key role in driving ageing. There …
Flavonoids as prospective compounds for anti-cancer therapy
D Ravishankar, AK Rajora, F Greco… - The international journal …, 2013 - Elsevier
Flavonoids, which are polyphenolic compounds, are a class of plant secondary metabolites
possessing a broad spectrum of pharmacological activity including anti-cancer activities …
possessing a broad spectrum of pharmacological activity including anti-cancer activities …
Distribution and biological activities of the flavonoid luteolin
M López-Lázaro - Mini reviews in medicinal chemistry, 2009 - ingentaconnect.com
Epidemiological evidence suggests that flavonoids may play an important role in the
decreased risk of chronic diseases associated with a diet rich in plant-derived foods …
decreased risk of chronic diseases associated with a diet rich in plant-derived foods …
[HTML][HTML] Senescence and senotherapeutics: a new field in cancer therapy
Cellular senescence is a stress response mechanism ensuring homeostasis. Its temporal
activation during embryonic development or normal adult life is linked with beneficial …
activation during embryonic development or normal adult life is linked with beneficial …
Recent advances in small organic molecules as DNA intercalating agents: Synthesis, activity, and modeling
A Rescifina, C Zagni, MG Varrica, V Pistarà… - European journal of …, 2014 - Elsevier
The interaction of small molecules with DNA plays an essential role in many biological
processes. As DNA is often the target for majority of anticancer and antibiotic drugs, study …
processes. As DNA is often the target for majority of anticancer and antibiotic drugs, study …
Dual agents loaded PLGA nanoparticles: systematic study of particle size and drug entrapment efficiency
X Song, Y Zhao, S Hou, F Xu, R Zhao, J He… - European journal of …, 2008 - Elsevier
PLGA nanoparticles simultaneously loaded with vincristine sulfate (VCR) and quercetin
(QC) were prepared via O/W emulsion solvent evaporation. Six independent processing …
(QC) were prepared via O/W emulsion solvent evaporation. Six independent processing …
Fruitful decade for antileishmanial compounds from 2002 to late 2011
Leishmaniasis, usually caused by the genus Leishmania, has not received the attention it
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …
deserves and in recent times has developed into a major health problem worldwide. 1, 2 …
Polyphenols and cancer cell growth
Polyphenols constitute an important group of phytochemicals that gained increased
research attention since it was found that they could affect cancer cell growth. Initial …
research attention since it was found that they could affect cancer cell growth. Initial …
Effective use of reducing agents and nanoparticle encapsulation in stabilizing catechins in alkaline solution
Catechins are an important class of dietary flavonoids with promising use as therapeutic
agents due to their potent antioxidant activity and diverse biological properties. However …
agents due to their potent antioxidant activity and diverse biological properties. However …
MAX1, a regulator of the flavonoid pathway, controls vegetative axillary bud outgrowth in Arabidopsis
G Lazar, HM Goodman - Proceedings of the National …, 2006 - National Acad Sciences
We show that MAX1, a specific repressor of vegetative axillary bud outgrowth in Arabidopsis,
acts a positive regulator of the flavonoid pathway, including 11 structural genes and the …
acts a positive regulator of the flavonoid pathway, including 11 structural genes and the …