Role of transgenic plants in agriculture and biopharming
At present, environmental degradation and the consistently growing population are two main
problems on the planet earth. Fulfilling the needs of this growing population is quite difficult …
problems on the planet earth. Fulfilling the needs of this growing population is quite difficult …
Emerging antibody products and Nicotiana manufacturing
KJ Whaley, A Hiatt, L Zeitlin - Human vaccines, 2011 - Taylor & Francis
Antibody based products are not widely available to address multiple global health
challenges due to high costs, limited manufacturing capacity, and long manufacturing lead …
challenges due to high costs, limited manufacturing capacity, and long manufacturing lead …
Chloroplast‐derived vaccine antigens confer dual immunity against cholera and malaria by oral or injectable delivery
A Davoodi‐Semiromi, M Schreiber… - Plant biotechnology …, 2010 - Wiley Online Library
Cholera and malaria are major diseases causing high mortality. The only licensed cholera
vaccine is expensive; immunity is lost in children within 3 years and adults are not fully …
vaccine is expensive; immunity is lost in children within 3 years and adults are not fully …
Carrot cells: a pioneering platform for biopharmaceuticals production
S Rosales-Mendoza, MA Tello-Olea - Molecular biotechnology, 2015 - Springer
Carrot (Daucus carota L.) is of importance in the molecular farming field as it constitutes the
first plant species approved to produce biopharmaceuticals for human use. In this review …
first plant species approved to produce biopharmaceuticals for human use. In this review …
Recent development and future prospects of plant-based vaccines
Background: Growing world population and continuous disease emergence have invited the
development of more efficient new vaccines against a range of diseases. Conventional …
development of more efficient new vaccines against a range of diseases. Conventional …
The last ten years of advancements in plant-derived recombinant vaccines against hepatitis B
YH Joung, SH Park, KB Moon, JH Jeon… - International Journal of …, 2016 - mdpi.com
Disease prevention through vaccination is considered to be the greatest contribution to
public health over the past century. Every year more than 100 million children are …
public health over the past century. Every year more than 100 million children are …
Using carrot cells as biofactories and oral delivery vehicles of LTB-Syn: A low-cost vaccine candidate against synucleinopathies
JI Arevalo-Villalobos, DOG Alonso… - Journal of …, 2020 - Elsevier
Synucleinopathies are conditions that remain with no available effective treatments thus far.
Immunotherapy is a possible path to fight against such pathologies by inducing antibodies …
Immunotherapy is a possible path to fight against such pathologies by inducing antibodies …
Assessing the efficiency of SBA-15 as a nanocarrier for diphtheria anatoxin
MK Rasmussen, HN Bordallo, MA Bordenalli… - Microporous and …, 2021 - Elsevier
SBA-15 ordered mesoporous silica can be considered a promising inorganic nanocarrier
with emerging potential as an oral vaccine adjuvant. In this study, we investigated its …
with emerging potential as an oral vaccine adjuvant. In this study, we investigated its …
Heterologous expression of recombinant proteins and their derivatives used as carriers for conjugate vaccines
YA Khodak - Biochemistry (Moscow), 2023 - Springer
Carrier proteins that provide an effective and long-term immune response to weak antigens
has become a real breakthrough in the disease prevention, making it available to a wider …
has become a real breakthrough in the disease prevention, making it available to a wider …
High-Level Production of Soluble Cross-Reacting Material 197 in Escherichia coli Cytoplasm Due to Fine Tuning of the Target Gene's mRNA Structure
YA Khodak, AY Ryazanova, II Vorobiev, AL Kovalchuk… - BioTech, 2023 - mdpi.com
Cross-reacting material 197 (CRM197) is a non-toxic mutant of the diphtheria toxin and is
widely used as a carrier protein in conjugate vaccines. This protein was first obtained from …
widely used as a carrier protein in conjugate vaccines. This protein was first obtained from …