The innate immune system includes several classes of pattern recognition receptors (PRRs),
including membrane-bound Toll-like receptors (TLRs) and nucleotide-binding …

Background Obesity is a leading contributor to numerous diseases, such as diabetes
mellitus, cardiovascular diseases, and cancers. Therefore, seeking effective and safe …

Various functions of the gut are regulated by sophisticated interactions among its functional
elements, including the gut microbiota. These microorganisms play a crucial role in …

The gut microbiota contributes to host energy metabolism, and altered gut microbiota has
been associated with obesity-related metabolic disorders. We previously reported that a …

Faecalibacterium prausnitzii is considered as one of the most important bacterial indicators
of a healthy gut. We studied the effects of oral F. prausnitzii treatment on high-fat fed mice …

Abstract Background Low-energy diets (LEDs) comprise commercially formulated food
products that provide between 800 and 1200 kcal/day (3.3–5 MJ/day) to aid body weight …

Next-generation sequencing (NGS) is currently the method of choice for analyzing gut
microbiota composition. As gut microbiota composition is a potential future target for clinical …

A rich body of literature indicates that environmental factors interact with the human
microbiome and influence its composition and functions contributing to the pathogenesis of …

Overweight and obesity increase the risk for a number of diseases, namely, cardiovascular
diseases, type 2 diabetes, dyslipidemia, premature death, non-alcoholic fatty liver disease …

Choline is an essential nutrient and methyl donor required for epigenetic regulation. Here,
we assessed the impact of gut microbial choline metabolism on bacterial fitness and host …