With the advent of multiomics, software capable of multidimensional enrichment analysis
has become increasingly crucial for uncovering gene set variations in biological processes …

The completion of the Human Genome Project has provided a foundational blueprint for
understanding human life. Nonetheless, understanding the intricate mechanisms through …

Spatial omics data are clustered to define both cell types and tissue domains. We present
Building Aggregates with a Neighborhood Kernel and Spatial Yardstick (BANKSY), an …

Spatial clustering, which shares an analogy with single-cell clustering, has expanded the
scope of tissue physiology studies from cell-centroid to structure-centroid with spatially …

Spatial transcriptomic techniques offer unprecedented insights into the molecular
organization of complex tissues. However, integrating cost-effectiveness, high throughput, a …

Advances in spatial omics technologies have improved the understanding of cellular
organization in tissues, leading to the generation of complex and heterogeneous data and …

The molecular and cellular organization of the primate cerebellum remains poorly
characterized. We obtained single-cell spatial transcriptomic atlases of macaque, marmoset …

Spatiomolecular analyses are key to study tissue functions and malfunctions. However, we
lack profiling tools for spatial transcriptomics that are easy to adopt, low cost and scalable in …

Plant scientists are rapidly integrating single-cell RNA sequencing (scRNA-seq) into their
workflows. Maximizing the potential of scRNA-seq requires a proper understanding of the …

Homeostatic plasticity maintains the stability of functional brain networks. The axon initial
segment (AIS), where action potentials start, undergoes dynamic adjustment to exert …