Coordination compounds-based drugs are crucial in targeting various diseases due to their
distinct structural order. They also show a significant role in biological systems, including …

Overcoming multidrug resistance (MDR) is one of the major challenges in cancer therapy. In
this respect, Schiff base-related compounds (bearing a R 1 R 2 Cdouble bondNR 3 bond) …

Abstract Pd (II) complexes (Pd1, Pd2, and Pd3) were synthesized for the first time using
asymmetric isatin bisthiocarbohydrazone ligands and PdCl2 (PPh3) 2. All complexes were …

The use of cisplatin and its derivatives in cancer treatment triggered the interest in metal-
containing complexes as potential novel anticancer agents. Palladium (II)-based complexes …

The biological activity of Cd compounds has been investigated scarce since Cd has been
recognized as a human carcinogen. However, the toxicity of cadmium is comparable to the …

Herein, we report the synthesis and biological evaluation of [Pd (L)(OH 2) Cl] complex
(where L= 2, 2′-(pyridin-2-ylmethylene) bis (5, 5-dimethylcyclohexane-1, 3-dione) as a …

Five new complexes of the palladium (II) ion (C1–C5) having the general formula [(PdL2)]
Cl2 with some 2-aminothiazoles (L1–L5), where L1= 2-amino-4-(3, 4-difluorophenyl) …

The burgeoning demand for novel cytotoxic drugs possessing improved bioavailability and
safety profiles has spurred the hybridization of various pharmacophores in the past decades …

Present paper reports on the interactions between four hydrazones derived from pyridoxal
and hydrazides of 2-furoic, thiophene-2-carboxylic, pyrazinoic and pyridine-3-carboxylic …

Metal-based inhibitors of histone deacetylases (HDAC), DNA topoisomerases (Topos) and
Epidermal Growth Factor Receptor (EGFR) have demonstrated their cytotoxic potential …