Proton pump inhibitor therapy for eosinophilic esophagitis: history, mechanisms, efficacy, and future directions

JP Franciosi, EB Mougey, ES Dellon… - Journal of asthma …, 2022 - Taylor & Francis
Over the past decade, the role of proton pump inhibitor (PPI) medication has evolved from a
diagnostic tool for Eosinophilic Esophagitis (EoE), by excluding patients with PPI responsive …

[HTML][HTML] Adverse effects associated with long-term use of proton pump inhibitors

NMP Maideen - Chonnam medical journal, 2023 - ncbi.nlm.nih.gov
Abstract Proton Pump Inhibitors are used widely to manage many gastric acid-related
conditions such as gastroesophageal disease, gastritis, esophagitis, Barrett's esophagus …

A large-scale genome-wide cross-trait analysis reveals shared genetic architecture between Alzheimer's disease and gastrointestinal tract disorders

EO Adewuyi, EK O'Brien, DR Nyholt, T Porter… - Communications …, 2022 - nature.com
Consistent with the concept of the gut-brain phenomenon, observational studies suggest a
relationship between Alzheimer's disease (AD) and gastrointestinal tract (GIT) disorders; …

Regular proton pump inhibitor use and incident dementia: population-based cohort study

P Zhang, Z Li, P Chen, A Zhang, Y Zeng, X Zhang… - BMC medicine, 2022 - Springer
Background To examine the association between regular use of proton pump inhibitors and
the risk of incident dementia, including dementia subtypes, and whether the association …

Cumulative use of proton pump inhibitors and risk of dementia: the atherosclerosis risk in communities study

CA Northuis, EJ Bell, PL Lutsey, KM George… - Neurology, 2023 - AAN Enterprises
Background and Objectives Studies on the association between proton pump inhibitor (PPI)
use and dementia report mixed results and do not examine the impact of cumulative PPI …

Association between non-alcoholic fatty liver disease and risk of stroke: a systematic review and meta-analysis

M Wang, BG Zhou, Y Zhang, XF Ren, L Li… - Frontiers in …, 2022 - frontiersin.org
Background/Objectives Recent observational studies have explored the association
between non-alcoholic fatty liver disease (NAFLD) and stroke with controversial results. We …

Proton pump inhibitors and the risk of Alzheimer's disease and non-Alzheimer's dementias

F Torres-Bondia, F Dakterzada, L Galván, M Buti… - Scientific reports, 2020 - nature.com
Proton pump inhibitors (PPIs) are among the most prescribed medications. Previous
epidemiological studies have presented contradictory results about PPIs and the risk of …

Do proton pump inhibitors increase the risk of dementia? A systematic review, meta‐analysis and bias analysis

N Ahn, M Nolde, E Krause, F Güntner… - British Journal of …, 2023 - Wiley Online Library
Aim Previous studies on the association between proton pump inhibitor (PPI) intake and the
increased risk of dementia has shown discrepancies in their conclusions. We aimed to …

Drugs in focus: proton pump inhibitors

MA Benninga, IJ Broekaert, F Gottrand… - Journal of pediatric …, 2021 - journals.lww.com
Proton pump inhibitors (PPIs) are amongst the most commonly prescribed drugs in infants
and children with the last decades witnessing a dramatic rise in their utilization. Although …

Is Helicobacter pylori infection associated with pancreatic cancer? A systematic review and meta-analysis of observational studies

BG Zhou, YZ Mei, JS Wang, JL Xia… - … in Chronic Disease, 2023 - journals.sagepub.com
Background and Objectives: Recent observational studies have investigated the association
between Helicobacter pylori (H. pylori) infection and pancreatic cancer with conflicting data …