[HTML][HTML] Bioactive peptides for boosting stem cell culture platform: Methods and applications

AA Dayem, SB Lee, KM Lim, A Kim, HJ Shin… - Biomedicine & …, 2023 - Elsevier
Peptides, short protein fragments, can emulate the functions of their full-length native
counterparts. Peptides are considered potent recombinant protein alternatives due to their …

Co-assembled supramolecular hydrogel of salvianolic acid b and a phosphopeptide for enhanced wound healing

X Huang, T Li, X Jiang, Z Wang, M Wang… - … Applied Materials & …, 2023 - ACS Publications
Supramolecular natural product gels (NPGs) have emerged as promising biomaterials for
scalable and adjustable drug delivery systems. These gels possess biocompatibility …

Biomimetic gland models with engineered stratagems

X Lin, L Sun, M Lu, Y Zhao - Research, 2023 - spj.science.org
As extensively distributed tissues throughout the human body, glands play a critical role in
various physiological processes. Therefore, the construction of biomimetic gland models in …

Ligand coupling and decoupling modulates stem cell fate

R Thangam, SY Kim, N Kang, H Hong… - Advanced Functional …, 2023 - Wiley Online Library
In natural microenvironment, various proteins containing adhesive ligands in fibrous and
non‐fibrous structures dynamically couple and decouple to regulate stem cell fate. Herein …

Receptor‐Level Proximity and Fastening of Ligands Modulates Stem Cell Differentiation

G Bae, MS Kim, R Thangam, TM Koo… - Advanced Functional …, 2022 - Wiley Online Library
Cellular adhesion is regulated by the binding of 10 nm sized integrin to Arg‐Gly‐Asp (RGD)
ligands present in extracellular matrix proteins. In this study, seed‐mediated growth of gold …

Remote magnetic microengineering and alignment of spheroids into 3D cellular fibers

N Demri, S Dumas, M Nguyen… - Advanced Functional …, 2022 - Wiley Online Library
Developing in vitro models that recapitulate the in vivo organization of living cells in a 3D
microenvironment is one of the current challenges in the field of tissue engineering. In …

Injectable peptide hydrogel encapsulation of mesenchymal stem cells improved viability, stemness, anti-inflammatory effects, and early stage wound healing

Q Li, G Qi, D Lutter, W Beard, CRS Souza… - Biomolecules, 2022 - mdpi.com
Human-adipose-derived mesenchymal stem cells (hADMSCs) are adult stem cells and are
relatively easy to access compared to other sources of mesenchymal stem cells (MSCs) …

Modeling development using microfluidics: bridging gaps to foster fundamental and translational research

S Sun, X Xue, J Fu - Current Opinion in Genetics & Development, 2023 - Elsevier
Highlights•Microfluidics can create and control chemical gradients to induce tissue
patterning.•Microfluidics can control material transport and physical environment.• …

Unlocking the Potential of Human-Induced Pluripotent Stem Cells: Cellular Responses and Secretome Profiles in Peptide Hydrogel 3D Culture

M Cui, W Wu, Q Li, G Qi, X Liu, J Bai, M Chen, P Li… - Cells, 2024 - mdpi.com
Human-induced pluripotent stem cells (hiPSCs) have shown great potential for human
health, but their growth and properties have been significantly limited by the traditional …

Nanofibril guided spheroid formation for enhanced pluripotency and differentiation of human induced pluripotent stem cells

W Cho, J Park, W Kim, W Mao, J Park, YM Jung… - Chemical Engineering …, 2024 - Elsevier
The spheroid formation derived from human-induced pluripotent stem cells (hiPSCs)
generates a three-dimensional (3D) microenvironment that fosters cell–cell interactions …