Research involving nonhuman primates (NHPs) has played a vital role in many of the
medical and scientific advances of the past century. NHPs are used because of their …

Dr David Barker first popularized the concept of fetal origins of adult disease (FOAD). Since
its inception, FOAD has received considerable attention. The FOAD hypothesis holds that …

Maternal obesity is thought to increase the offspring's risk of juvenile obesity and metabolic
diseases; however, the mechanism (s) whereby excess maternal nutrition affects fetal …

There are many instances in life when the environment plays a critical role in the health
outcomes of an individual, yet none more so than those experienced in fetal and neonatal …

Pathological fetal growth is associated with perinatal morbidity and the development of
diabetes and cardiovascular disease later in life. Placental nutrient transport is a primary …

The developmental origins of health and disease theory is based on evidence that a
suboptimal environment during fetal and neonatal development can significantly impact the …

A major challenge for understanding susceptibility to common human diseases is
determining genetic and environmental factors that influence mechanisms underlying …

Prenatal origins of adult disease : Current Opinion in Obstetrics and Gynecology Prenatal
origins of adult disease : Current Opinion in Obstetrics and Gynecology Log in or Register …

Caloric restriction (CR), defined as decreased nutrient intake without causing malnutrition,
has been documented to increase both health and lifespan across numerous organisms …

In humans born at term, maximal nephron number is reached by the time nephrogenesis is
completed—at approximately 36 weeks' gestation. The number of nephrons does not …