Apoptosis in Alzheimer's disease: insight into the signaling pathways and therapeutic avenues
S Kumari, R Dhapola, DHK Reddy - Apoptosis, 2023 - Springer
Alzheimer's disease (AD) is characterized by the accumulation of hyperphosphorylated tau
and amyloid-β (Aβ) protein resulting in synaptic loss and apoptosis. Aβ and tau deposition …
and amyloid-β (Aβ) protein resulting in synaptic loss and apoptosis. Aβ and tau deposition …
Imaging the substantia nigra in Parkinson disease and other Parkinsonian syndromes
Parkinson disease is characterized by dopaminergic cell loss in the substantia nigra of the
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …
midbrain. There are various imaging markers for Parkinson disease. Recent advances in …
The detection of Parkinson disease using the genetic algorithm and SVM classifier
The speech signal is like the black box of human beings where much information is hidden.
The treatment of this signal provides us with the speaker's identity. In a way, it is similar to an …
The treatment of this signal provides us with the speaker's identity. In a way, it is similar to an …
[HTML][HTML] Why senescent cells are resistant to apoptosis: an insight for senolytic development
L Hu, H Li, M Zi, W Li, J Liu, Y Yang, D Zhou… - Frontiers in Cell and …, 2022 - frontiersin.org
Cellular senescence is a process that leads to a state of irreversible cell growth arrest
induced by a variety of intrinsic and extrinsic stresses. Senescent cells (SnCs) accumulate …
induced by a variety of intrinsic and extrinsic stresses. Senescent cells (SnCs) accumulate …
Treatment of autonomic dysfunction in Parkinson disease and other synucleinopathies
JA Palma, H Kaufmann - Movement Disorders, 2018 - Wiley Online Library
Dysfunction of the autonomic nervous system afflicts most patients with Parkinson disease
and other synucleinopathies such as dementia with Lewy bodies, multiple system atrophy …
and other synucleinopathies such as dementia with Lewy bodies, multiple system atrophy …
Synaptic changes in Parkinson disease assessed with in vivo imaging
D Matuskey, S Tinaz, KC Wilcox… - Annals of …, 2020 - Wiley Online Library
Objective Parkinson disease is characterized by motor and nonmotor symptoms, reduced
striatal dopamine signaling, and loss of dopamine neurons in the substantia nigra. It is now …
striatal dopamine signaling, and loss of dopamine neurons in the substantia nigra. It is now …
[HTML][HTML] Programmed cell death in diabetic nephropathy: a review of apoptosis, autophagy, and necroptosis
NS Erekat - Medical Science Monitor: International Medical Journal …, 2022 - ncbi.nlm.nih.gov
Diabetic nephropathy is a common complication of type I and type II diabetes, in which renal
glomeruli are destroyed, resulting in renal damage, proteinuria, and hypertension …
glomeruli are destroyed, resulting in renal damage, proteinuria, and hypertension …
SGK1 inhibition in glia ameliorates pathologies and symptoms in Parkinson disease animal models
OC Kwon, JJ Song, Y Yang, SH Kim, JY Kim… - EMBO Molecular …, 2021 - embopress.org
Astrocytes and microglia are brain‐resident glia that can establish harmful inflammatory
environments in disease contexts and thereby contribute to the progression of neuronal loss …
environments in disease contexts and thereby contribute to the progression of neuronal loss …
Dihydroxy-metabolites of dihomo-γ-linolenic acid drive ferroptosis-mediated neurodegeneration
M Sarparast, E Pourmand, J Hinman… - ACS Central …, 2023 - ACS Publications
Even after decades of research, the mechanism of neurodegeneration remains
understudied, hindering the discovery of effective treatments for neurodegenerative …
understudied, hindering the discovery of effective treatments for neurodegenerative …
[HTML][HTML] Role of induced programmed cell death in the chemopreventive potential of apigenin
JY Jang, B Sung, ND Kim - International Journal of Molecular Sciences, 2022 - mdpi.com
The flavonoid apigenin (4′, 5, 7-trihydroxyflavone), which is one of the most widely
distributed phytochemicals in the plant kingdom, is one of the most thoroughly investigated …
distributed phytochemicals in the plant kingdom, is one of the most thoroughly investigated …