X-ray-based 3D virtual histology—Adding the next dimension to histological analysis

J Albers, S Pacilé, MA Markus, M Wiart… - Molecular Imaging and …, 2018 - Springer
Histology and immunohistochemistry of thin tissue sections have been the standard
diagnostic procedure in many diseases for decades. This method is highly specific for …

Analytical approaches for characterizing and quantifying engineered nanoparticles in biological matrices from an (eco) toxicological perspective: old challenges, new …

FA Monikh, L Chupani, MG Vijver, M Vancová… - Science of The Total …, 2019 - Elsevier
To promote the safer by design strategy and assess environmental risks of engineered
nanoparticles (ENPs), it is essential to understand the fate of ENPs within organisms. This …

[HTML][HTML] Injection of high dose botulinum-toxin A leads to impaired skeletal muscle function and damage of the fibrilar and non-fibrilar structures

J Pingel, MS Nielsen, T Lauridsen, K Rix, M Bech… - Scientific reports, 2017 - nature.com
Abstract Botulinum-toxin A (BoNT/A) is used for a wide range of conditions. Intramuscular
administration of BoNT/A inhibits the release of acetylcholine at the neuromuscular junction …

Nano-CT as tool for characterization of dental resin composites

HJ Haugen, SB Qasim, JP Matinlinna, P Vallittu… - Scientific reports, 2020 - nature.com
Technological advances have made it possible to examine dental resin composites using
3D nanometer resolution. This investigation aims to characterize existing dental nano-hybrid …

Use of metal-based contrast agents for in vivo MR and CT imaging of phagocytic cells in neurological pathologies

M Wiart, C Tavakoli, V Hubert, I Hristovska… - Journal of Neuroscience …, 2023 - Elsevier
The activation of phagocytic cells is a hallmark of many neurological diseases. Imaging them
in their 3-dimensional cerebral environment over time is crucial to better understand their …

Brain virtual histology with X-ray phase-contrast tomography Part II: 3D morphologies of amyloid-β plaques in Alzheimer's disease models

M Chourrout, M Roux, C Boisvert, C Gislard… - Biomedical optics …, 2022 - opg.optica.org
While numerous transgenic mouse strains have been produced to model the formation of
amyloid-β (Aβ) plaques in the brain, efficient methods for whole-brain 3D analysis of Aβ …

Alterations of mass density and 3D osteocyte lacunar properties in bisphosphonate-related osteonecrotic human jaw bone, a synchrotron µCT study

B Hesse, M Langer, P Varga, A Pacureanu, P Dong… - PloS one, 2014 - journals.plos.org
Osteonecrosis of the jaw, in association with bisphosphonates (BRONJ) used for treating
osteoporosis or cancer, is a severe and most often irreversible side effect whose underlying …

Evaluation of phase retrieval approaches in magnified X-ray phase nano computerized tomography applied to bone tissue

B Yu, L Weber, A Pacureanu, M Langer, C Olivier… - Optics …, 2018 - opg.optica.org
X-ray phase contrast imaging offers higher sensitivity compared to conventional X-ray
attenuation imaging and can be simply implemented by propagation when using a partially …

Brain virtual histology with X-ray phase-contrast tomography Part I: whole-brain myelin mapping in white-matter injury models

M Chourrout, H Rositi, E Ong, V Hubert… - Biomedical optics …, 2022 - opg.optica.org
White-matter injury leads to severe functional loss in many neurological diseases. Myelin
staining on histological samples is the most common technique to investigate white-matter …

Albumin-functionalized iron oxide nanoparticles for theranostics: engineering and long-term in situ imaging

AV Bychkova, MN Yakunina, MV Lopukhova… - Pharmaceutics, 2022 - mdpi.com
Magnetic nanosystems (MNSs) consisting of magnetic iron oxide nanoparticles (IONPs)
coated by human serum albumin (HSA), commonly used as a component of hybrid …