[HTML][HTML] PCSK9: a multi-faceted protein that is involved in cardiovascular biology
SS Sundararaman, Y Döring, EPC van Der Vorst - Biomedicines, 2021 - mdpi.com
Pro-protein convertase subtilisin/kexin type 9 (PCSK9) is secreted mostly by hepatocytes
and to a lesser extent by the intestine, pancreas, kidney, adipose tissue, and vascular cells …
and to a lesser extent by the intestine, pancreas, kidney, adipose tissue, and vascular cells …
[HTML][HTML] PCSK9 inhibition and cholesterol homeostasis in insulin producing β-cells
G Päth, N Perakakis, CS Mantzoros… - Lipids in Health and …, 2022 - Springer
Low-density lipoprotein cholesterol (LDL-C) plays a central role in the pathology of
atherosclerotic cardiovascular disease. For decades, the gold standard for LDL-C lowering …
atherosclerotic cardiovascular disease. For decades, the gold standard for LDL-C lowering …
Pseudorabies virus upregulates low-density lipoprotein receptors to facilitate viral entry
YX Ma, YJ Chai, YQ Han, SB Zhao, GY Yang… - Journal of …, 2024 - Am Soc Microbiol
Pseudorabies virus (PRV) is the causative agent of Aujeszky's disease in pigs. The low-
density lipoprotein receptor (LDLR) is a transcriptional target of the sterol-regulatory element …
density lipoprotein receptor (LDLR) is a transcriptional target of the sterol-regulatory element …
Molecular and cellular biology of PCSK9: impact on glucose homeostasis
SER Tchéoubi, CD Akpovi, F Coppée… - Journal of drug …, 2022 - Taylor & Francis
Proprotein convertase substilisin/kexin 9 (PCSK9) inhibitors (PCSK9i) revolutionised the
lipid-lowering therapy. However, a risk of type 2 diabetes mellitus (T2DM) is evoked under …
lipid-lowering therapy. However, a risk of type 2 diabetes mellitus (T2DM) is evoked under …
[HTML][HTML] Insight into the role of PCSK9 in glucose metabolism
J Xu, T Wang, H Shu, S Shi, L Tao, JJ Li - Clinica Chimica Acta, 2023 - Elsevier
Diabetes mellitus (DM) is strongly associated with an increased risk of atherosclerotic
cardiovascular disease (ASCVD). Proprotein convertase subtilisin/kexin type 9 (PCSK9) was …
cardiovascular disease (ASCVD). Proprotein convertase subtilisin/kexin type 9 (PCSK9) was …
The biological relevance of PCSK9: when less is better…
M Mbikay, M Chrétien - Biochemistry and Cell Biology, 2022 - cdnsciencepub.com
Proprotein Convertase Subtilisin/Kexin-type 9 (PCSK9) is a circulating negative regulator of
hepatic low-density lipoprotein receptor (LDLR), which clears cholesterol from blood. Gain …
hepatic low-density lipoprotein receptor (LDLR), which clears cholesterol from blood. Gain …
[HTML][HTML] C679X loss-of-function PCSK9 variant is associated with lower fasting glucose in black South African adolescents: Birth to Twenty Plus Cohort
T Chikowore, V Sahibdeen, LM Hendry… - Journal of clinical & …, 2019 - Elsevier
Aim To evaluate the association between loss-of-function (LOF) PCSK9 variants
(A433T/rs28362263 and C679X/rs28362286) and biomarkers of cardiometabolic risk …
(A433T/rs28362263 and C679X/rs28362286) and biomarkers of cardiometabolic risk …
[HTML][HTML] Strengthening Bioinformatics and Genomics Analysis Skills in Africa for Attainment of the Sustainable Development Goals: report of the 2nd conference of the …
The second conference of the Nigerian Bioinformatics and Genomics Network (NBGN21)
was held from October 11 to October 13, 2021. The event was organized by the Nigerian …
was held from October 11 to October 13, 2021. The event was organized by the Nigerian …
[PDF][PDF] PCSK9: A Multi-Faceted Protein That Is Involved in Cardiovascular Biology. Biomedicines 2021, 9, 793
SS Sundararaman, Y Döring, EPC van der Vorst - 2021 - publications.rwth-aachen.de
Pro-protein convertase subtilisin/kexin type 9 (PCSK9) is secreted mostly by hepatocytes
and to a lesser extent by the intestine, pancreas, kidney, adipose tissue, and vascular cells …
and to a lesser extent by the intestine, pancreas, kidney, adipose tissue, and vascular cells …
[引用][C] The role of PCSK9 in glomerular lipid accumulation and renal injury in diabetic kidney disease
윤창연 - 2019 - Graduate School, Yonsei University