[HTML][HTML] Tracking cancer progression: From circulating tumor cells to metastasis

F Castro-Giner, N Aceto - Genome medicine, 2020 - Springer
The analysis of circulating tumor cells (CTCs) is an outstanding tool to provide insights into
the biology of metastatic cancers, to monitor disease progression and with potential for use …

[HTML][HTML] Selected in situ hybridization methods: principles and application

D Veselinyová, J Mašlanková, K Kalinová, H Mičková… - Molecules, 2021 - mdpi.com
We are experiencing rapid progress in all types of imaging techniques used in the detection
of various numbers and types of mutation. In situ hybridization (ISH) is the primary technique …

Applications of advanced technologies for detecting genomic structural variation

V Laufer, TW Glover, TE Wilson - Mutation Research/Reviews in Mutation …, 2023 - Elsevier
Chromosomal structural variation (SV) encompasses a heterogenous class of genetic
variants that exerts strong influences on human health and disease. Despite their …

[HTML][HTML] Application of a multiplex ligation-dependent probe amplification-based next-generation sequencing approach for the detection of pathogenesis of Duchenne …

Y Yang, C Xia, X Song, X Tang, X Nie, W Xu, C Du… - Molecular …, 2024 - Springer
Both Duchenne muscular dystrophy (DMD; OMIM no. 310200) and spinal muscular atrophy
(SMA; OMIM no. 253300/253550/253400/271150) are genetic disorders characterized by …

[HTML][HTML] Application of fluorescence In situ hybridization (FISH) in oral microbial detection

J Gu, H Wang, M Zhang, Y Xiong, L Yang, B Ren… - Pathogens, 2022 - mdpi.com
Varieties of microorganisms reside in the oral cavity contributing to the occurrence and
development of microbes associated with oral diseases; however, the distribution and in situ …

[HTML][HTML] Quality control of cell lines using DNA as target

JA Carrillo-Ávila, P Catalina, R Aguilar-Quesada - DNA, 2022 - mdpi.com
Cell lines are a widely used pre-clinical models for biomedical research. The accessibility
and the relative simplicity of facilities necessary for the use of cell lines, along with the large …

Hierarchal Bayes model with AlexNet for characterization of M-FISH chromosome images

VS Kanimozhi, M Balasubramani… - Medical & Biological …, 2021 - Springer
The analysis of chromosomes is a significant and challenging task for clinical diagnosis and
biological research. The technique based on color imaging is a multiplex fluorescent in situ …

Somatic focal copy number gains of noncoding regions of receptor tyrosine kinase genes in treatment-resistant epilepsy

V Vasudevaraja, JH Rodriguez… - … of Neuropathology & …, 2021 - academic.oup.com
Epilepsy is a heterogenous group of disorders defined by recurrent seizure activity due to
abnormal synchronized activity of neurons. A growing number of epilepsy cases are …

[HTML][HTML] Fluorescent In Situ Hybridization for the Detection of Intracellular Bacteria in Companion Animals

MJ Rolph, P Bolfa, SM Cavanaugh, KE Rolph - Veterinary Sciences, 2024 - mdpi.com
Simple Summary Bacterial infections have traditionally been identified by culture; however,
with advances in the understanding of the role of bacteria in disease, it is recognized that …

Circulating tumor cell characterization and classification by novel combinatorial dual-color (CoDuCo) in situ hybridization and supervised machine learning

L Bonstingl, M Zinnegger, K Sallinger, K Pankratz… - bioRxiv, 2024 - biorxiv.org
Metastatic prostate cancer is a highly heterogeneous and dynamic disease and practicable
tools for patient stratification and resistance monitoring are urgently needed. Liquid biopsy …