Mycobacterium tuberculosis complex (MTBC) refers to a group of mycobacteria
encompassing nine members of closely related species that causes tuberculosis in animals …

Rapid diagnosis is one key pillar to end tuberculosis (TB). Point-of-care tests (POCTs)
facilitate early detection, immediate treatment, and reduced transmission of TB disease. This …

Background Tuberculosis is usually treated with a 6-month rifampin-based regimen.
Whether a strategy involving shorter initial treatment may lead to similar outcomes is …

Background Targeted preventive therapy for individuals at highest risk of incident
tuberculosis might impact the epidemic by interrupting transmission. We tested performance …

Aim: Provide an overview of current available LTBI diagnostic test including updates, future
developments and perspectives. Results: There is currently no test for the direct …

Background We hypothesised that host-response biomarkers of viral infections might
contribute to early identification of individuals infected with SARS-CoV-2, which is critical to …

Viral infections induce a conserved host response distinct from bacterial infections. We
hypothesized that the conserved response is associated with disease severity and is distinct …

Tuberculosis is an airborne disease caused by Mycobacterium tuberculosis (Mtb) and can
manifest both pulmonary and extrapulmonary disease, including ocular tuberculosis (OTB) …

Background A rapid, blood-based triage test that allows targeted investigation for
tuberculosis at the point of care could shorten the time to tuberculosis treatment and reduce …

Background The relationship between tuberculosis (TB), one of the leading infectious
causes of death worldwide, and the microbiome, which is critical for health, is poorly …