Fast fluorescence lifetime imaging techniques: A review on challenge and development

X Liu, D Lin, W Becker, J Niu, B Yu, L Liu… - Journal of Innovative …, 2019 - World Scientific
Fluorescence lifetime imaging microscopy (FLIM) is increasingly used in biomedicine,
material science, chemistry, and other related research fields, because of its advantages of …

CMOS SPADs: Design issues and research challenges for detectors, circuits, and arrays

DP Palubiak, MJ Deen - IEEE Journal of Selected Topics in …, 2014 - ieeexplore.ieee.org
Solid-state single photon detectors are playing a significant role in the development of high-
performance single-photon imaging systems for fluorescence lifetime imaging, time-of-flight …

0.5 billion events per second time correlated single photon counting using CMOS SPAD arrays

N Krstajić, S Poland, J Levitt, R Walker, A Erdogan… - Optics letters, 2015 - opg.optica.org
We present a digital architecture for fast acquisition of time correlated single photon counting
(TCSPC) events from a 32× 32 complementary metal oxide semiconductor (CMOS) single …

Time‐domain microfluidic fluorescence lifetime flow cytometry for high‐throughput F örster resonance energy transfer screening

J Nedbal, V Visitkul, E Ortiz‐Zapater… - Cytometry Part …, 2015 - Wiley Online Library
Sensing ion or ligand concentrations, physico‐chemical conditions, and molecular
dimerization or conformation change is possible by assays involving fluorescent lifetime …

Picosecond time-resolved imaging using SPAD cameras

G Gariepy, J Leach, R Warburton… - Emerging Imaging …, 2016 - spiedigitallibrary.org
The recent development of 2D arrays of single-photon avalanche diodes (SPAD) has driven
the development of applications based on the ability to capture light in motion. Such arrays …

Advanced fluorescence lifetime imaging algorithms for CMOS single-photon sensor based multi-focal multi-photon microscopy

DDU Li, S Poland, S Coelho, D Tyndall… - 2013 35th Annual …, 2013 - ieeexplore.ieee.org
We have developed a fast hardware friendly bi-exponential fluorescence lifetime algorithm
suitable for 2D CMOS single-photon avalanche diode (SPAD) arrays. The performance of …

[PDF][PDF] Time Resolved Light Sheet Microscopy

DJ O'Brien - 2019 - discovery.dundee.ac.uk
Understanding and identifying critical protein-protein interactions is just one of the key
outcomes in biological research. It can help to confirm key cellular interactions, which in …

[PDF][PDF] Picosecond time-resolved imaging using SPAD array cameras

G Gariepya, J Leacha, R Warburtona, S Chana… - Proc. of SPIE Vol - physics.gla.ac.uk
The recent development of 2D arrays of single-photon avalanche diodes (SPAD) has driven
the development of applications based on the ability to capture light in motion. Such arrays …