Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

Breast cancer is one of the leading causes of mortality in females. Over the past decades,
intensive efforts have been made to uncover the pathogenesis of breast cancer. Interleukin …

Abstract Interleukin-6 (IL-6) is a pleiotropic cytokine with significant functions in the
regulation of the immune system. As a potent pro-inflammatory cytokine, IL-6 plays a pivotal …

Interleukin-6 (IL-6) is a multifunctional cytokine which plays an important role in a wide
range of biologic activities in different types of cell including tumor cells. IL-6 is involved in …

Cancer arises in the context of an in vivo tumor microenvironment. This microenvironment is
both a cause and consequence of tumorigenesis. Tumor and host cells co-evolve …

Background: Interleukin-6 (IL-6) has an important role in cancer progression, and high levels
of plasma IL-6 are correlated with a poor prognosis in a variety of cancers. It has also been …

The consequences of prostate cancer metastasis remain severe, with huge impact on the
mortality and overall quality of life of affected patients. Despite the convoluted interplay and …

Interleukin-6 is an inflammatory cytokine with wide-ranging biological effects. It has been
widely demonstrated that neuroinflammation plays a critical role in the development of …

Environmental and genetic aspects are reflected in the development of prostate cancer. In
this context, there is growing evidence that chronic inflammation is involved in the regulation …

The androgen receptor (AR), ligand-induced transcription factor, is expressed in primary
prostate cancer and in metastases. AR regulates multiple cellular events, proliferation …