Clinical trials with mesenchymal stem cells: an update
T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …
regenerative properties and ability to differentiate into diverse cell lineages, have generated …
Brain photobiomodulation therapy: a narrative review
Brain photobiomodulation (PBM) therapy using red to near-infrared (NIR) light is an
innovative treatment for a wide range of neurological and psychological conditions. Red/NIR …
innovative treatment for a wide range of neurological and psychological conditions. Red/NIR …
Chromatographically isolated CD63+CD81+ extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI
Extracellular vesicles (EVs) secreted by cells present an attractive strategy for developing
new therapies, but progress in the field is limited by several issues: The quality of the EVs …
new therapies, but progress in the field is limited by several issues: The quality of the EVs …
Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications
Mesenchymal stem cells (MSCs) are primary candidates in cell therapy and tissue
engineering and are being tested in clinical trials for a wide range of diseases. Originally …
engineering and are being tested in clinical trials for a wide range of diseases. Originally …
[HTML][HTML] The stem cell secretome and its role in brain repair
Compelling evidence exists that non-haematopoietic stem cells, including mesenchymal
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …
[HTML][HTML] Chondrocyte and mesenchymal stem cell-based therapies for cartilage repair in osteoarthritis and related orthopaedic conditions
Osteoarthritis (OA) represents a final and common pathway for all major traumatic insults to
synovial joints. OA is the most common form of degenerative joint disease and a major …
synovial joints. OA is the most common form of degenerative joint disease and a major …
Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?
The low regeneration potential of the central nervous system (CNS) represents a challenge
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …
Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer's mice
G Santamaria, E Brandi, PL Vitola, F Grandi… - Cell Death & …, 2021 - nature.com
The multiplicity of systems affected in Alzheimer's disease (AD) brains calls for multi-target
therapies. Although mesenchymal stem cells (MSC) are promising candidates, their clinical …
therapies. Although mesenchymal stem cells (MSC) are promising candidates, their clinical …
[HTML][HTML] Mesenchymal stromal cell-derived extracellular vesicles afford neuroprotection by modulating PI3K/AKT pathway and calcium oscillations
EA Turovsky, VV Golovicheva… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSC) are widely recognized as potential effectors in
neuroprotective therapy. The protective properties of MSC were considered to be associated …
neuroprotective therapy. The protective properties of MSC were considered to be associated …
Preterm brain injury, antenatal triggers, and therapeutics: timing is key
DRMG Ophelders, R Gussenhoven, L Klein… - Cells, 2020 - mdpi.com
With a worldwide incidence of 15 million cases, preterm birth is a major contributor to
neonatal mortality and morbidity, and concomitant social and economic burden Preterm …
neonatal mortality and morbidity, and concomitant social and economic burden Preterm …