Clinical trials with mesenchymal stem cells: an update

T Squillaro, G Peluso, U Galderisi - Cell transplantation, 2016 - journals.sagepub.com
In the last year, the promising features of mesenchymal stem cells (MSCs), including their
regenerative properties and ability to differentiate into diverse cell lineages, have generated …

Brain photobiomodulation therapy: a narrative review

F Salehpour, J Mahmoudi, F Kamari… - Molecular …, 2018 - Springer
Brain photobiomodulation (PBM) therapy using red to near-infrared (NIR) light is an
innovative treatment for a wide range of neurological and psychological conditions. Red/NIR …

Chromatographically isolated CD63+CD81+ extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI

D Kim, H Nishida, SY An, AK Shetty… - Proceedings of the …, 2016 - National Acad Sciences
Extracellular vesicles (EVs) secreted by cells present an attractive strategy for developing
new therapies, but progress in the field is limited by several issues: The quality of the EVs …

Three-dimensional aggregates of mesenchymal stem cells: cellular mechanisms, biological properties, and applications

S Sart, AC Tsai, Y Li, T Ma - Tissue Engineering Part B: Reviews, 2014 - liebertpub.com
Mesenchymal stem cells (MSCs) are primary candidates in cell therapy and tissue
engineering and are being tested in clinical trials for a wide range of diseases. Originally …

[HTML][HTML] The stem cell secretome and its role in brain repair

D Drago, C Cossetti, N Iraci, E Gaude, G Musco… - Biochimie, 2013 - Elsevier
Compelling evidence exists that non-haematopoietic stem cells, including mesenchymal
(MSCs) and neural/progenitor stem cells (NPCs), exert a substantial beneficial and …

[HTML][HTML] Chondrocyte and mesenchymal stem cell-based therapies for cartilage repair in osteoarthritis and related orthopaedic conditions

A Mobasheri, G Kalamegam, G Musumeci, ME Batt - Maturitas, 2014 - Elsevier
Osteoarthritis (OA) represents a final and common pathway for all major traumatic insults to
synovial joints. OA is the most common form of degenerative joint disease and a major …

Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?

FG Teixeira, MM Carvalho, N Sousa… - Cellular and Molecular …, 2013 - Springer
The low regeneration potential of the central nervous system (CNS) represents a challenge
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …

Intranasal delivery of mesenchymal stem cell secretome repairs the brain of Alzheimer's mice

G Santamaria, E Brandi, PL Vitola, F Grandi… - Cell Death & …, 2021 - nature.com
The multiplicity of systems affected in Alzheimer's disease (AD) brains calls for multi-target
therapies. Although mesenchymal stem cells (MSC) are promising candidates, their clinical …

[HTML][HTML] Mesenchymal stromal cell-derived extracellular vesicles afford neuroprotection by modulating PI3K/AKT pathway and calcium oscillations

EA Turovsky, VV Golovicheva… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Mesenchymal stromal cells (MSC) are widely recognized as potential effectors in
neuroprotective therapy. The protective properties of MSC were considered to be associated …

Preterm brain injury, antenatal triggers, and therapeutics: timing is key

DRMG Ophelders, R Gussenhoven, L Klein… - Cells, 2020 - mdpi.com
With a worldwide incidence of 15 million cases, preterm birth is a major contributor to
neonatal mortality and morbidity, and concomitant social and economic burden Preterm …