Calcium (Ca2+) is a unique mineral that serves as both a nutrient and a signal in all
eukaryotes. To maintain Ca2+ homeostasis for both nutrition and signaling purposes, the …

The calcium-based intracellular signalling system is used ubiquitously to couple
extracellular stimuli to their characteristic intracellular responses. It is becoming clear from …

The transient receptor potential superfamily of ion channels (TRP channels) is widely
recognized for the roles its members play in sensory nervous systems. However, the …

Ion channels control the sperm ability to fertilize the egg by regulating sperm maturation in
the female reproductive tract and by triggering key sperm physiological responses required …

Fungi are ecologically important heterotrophs that have radiated into most niches on Earth
and fulfil key ecological services. Despite intense interest in their origins, major genomic …

Calcium (Ca2+) release from intracellular stores controls numerous cellular processes,
including cardiac and skeletal muscle contraction, synaptic transmission and metabolism …

The functions of TRP channels have primarily been characterized in model organisms within
a limited evolutionary context. We thus characterize the TRP channels in choanoflagellate …

Sensory receptors are at the interface between an organism and its environment and thus
represent key sites for biological innovation. Here, we survey major sensory receptor …

Simple Summary In this review, recent discoveries regarding transient receptor potential are
discussed and analyzed to comprehend their role in the thermoregulatory mechanisms of …

All living cells interact dynamically with a constantly changing world. Eukaryotes, in
particular, evolved radically new ways to sense and react to their environment. These …