Clinical trials in amyotrophic lateral sclerosis: why so many negative trials and how can trials be improved?
H Mitsumoto, BR Brooks, V Silani - The Lancet Neurology, 2014 - thelancet.com
Amyotrophic lateral sclerosis (ALS) is one of the most rapidly progressive
neurodegenerative diseases of unknown cause. Riluzole is the only drug that slows disease …
neurodegenerative diseases of unknown cause. Riluzole is the only drug that slows disease …
Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease
Symptomatic treatments for amyotrophic lateral sclerosis/motor neuron disease - Ng, L - 2017 |
Cochrane Library Skip to Content Cookies Our site uses cookies to improve your experience …
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Impact of expiratory strength training in amyotrophic lateral sclerosis: Results of a randomized, sham‐controlled trial
EK Plowman, L Tabor‐Gray, KM Rosado… - Muscle & …, 2019 - Wiley Online Library
Introduction The purpose of this study was to determine the impact of an in‐home expiratory
muscle strength training (EMST) program on pulmonary, swallow, and cough function in …
muscle strength training (EMST) program on pulmonary, swallow, and cough function in …
Physical activity and lifestyle modifications in the treatment of neurodegenerative diseases
JA Santiago, JA Potashkin - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Neurodegenerative diseases have reached alarming numbers in the past decade.
Unfortunately, clinical trials testing potential therapeutics have proven futile. In the absence …
Unfortunately, clinical trials testing potential therapeutics have proven futile. In the absence …
Therapeutic exercise for people with amyotrophic lateral sclerosis or motor neuron disease
V Dal Bello‐Haas, JM Florence - Cochrane Database of …, 2013 - cochranelibrary.com
Background Despite the high incidence of muscle weakness in individuals with amyotrophic
lateral sclerosis (ALS) or motor neuron disease (MND), the effects of exercise in this …
lateral sclerosis (ALS) or motor neuron disease (MND), the effects of exercise in this …
Disease-modifying and symptomatic treatment of amyotrophic lateral sclerosis
J Dorst, AC Ludolph, A Huebers - Therapeutic advances in …, 2018 - journals.sagepub.com
In this review, we summarize the most important recent developments in the treatment of
amyotrophic lateral sclerosis (ALS). In terms of disease-modifying treatment options, several …
amyotrophic lateral sclerosis (ALS). In terms of disease-modifying treatment options, several …
Rehabilitation in amyotrophic lateral sclerosis: why it matters
S Majmudar, J Wu, S Paganoni - Muscle & nerve, 2014 - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease that results in a
constellation of problematic symptoms and a high patient and caregiver burden …
constellation of problematic symptoms and a high patient and caregiver burden …
Canadian best practice recommendations for the management of amyotrophic lateral sclerosis
C Shoesmith, A Abrahao, T Benstead, M Chum… - Cmaj, 2020 - Can Med Assoc
The care and management of patients with ALS should always be patient focused, with
attention to holistic and emotional aspects of well-being. It is the patient who ultimately …
attention to holistic and emotional aspects of well-being. It is the patient who ultimately …
Mitophagy and the brain
NS Swerdlow, HM Wilkins - International journal of molecular sciences, 2020 - mdpi.com
Stress mechanisms have long been associated with neuronal loss and neurodegenerative
diseases. The origin of cell stress and neuronal loss likely stems from multiple pathways …
diseases. The origin of cell stress and neuronal loss likely stems from multiple pathways …
Mechanisms of exercise as a preventative measure to muscle wasting
Skeletal muscle is the most abundant tissue in healthy individuals and it has important roles
in health beyond voluntary movement. The overall mass and energy requirements of …
in health beyond voluntary movement. The overall mass and energy requirements of …