Synthetic organic electrosynthesis has grown in the past few decades by achieving many
valuable transformations for synthetic chemists. Although electrocatalysis has been popular …

Transition metal-catalyzed direct functionalization of C–H bonds is one of the key emerging
strategies that is currently attracting tremendous attention with the aim to provide alternative …

Herein, a regioselective, late-stage two-step arene halogenation method is reported. We
propose how unusual Ni (I)/(III) catalysis is enabled by a combination of aryl thianthrenium …

The high utility of halogenated organic compounds has prompted the development of a vast
number of transformations which install the carbon–halogen motif. Traditional routes to …

The first cobalt-catalyzed cyanation, halogenation, and allylation via C–H activation have
been realized. These formal SN-type reactions generate valuable (hetero) aryl/alkenyl …

Effective methodology to functionalize C–H bonds requires overcoming the key challenge of
differentiating among the multitude of C–H bonds that are present in complex organic …

The development of methods for the direct conversion of carbonshydrogen bonds into
carbon-oxygen, carbon-halogen, carbon-nitrogen, carbon-sulfur, and carbon-carbon bonds …

The use of directing groups has proven to be a successful strategy to enhance reactivity and
control selectivity in C–H functionalization reactions. In the past decade, a multitude of new …

In chemistry, a nucleophile is a molecule or ion with a lone pair of electrons. It donates both
bonding electrons to its reaction partner (the electrophile) when forming a chemical bond. 1 …

The use of coordinating moieties as directing groups for the functionalization of aromatic C
H bonds has become an established tool to enhance reactivity and induce regioselectivity …