[HTML][HTML] Blood-brain barrier: from physiology to disease and back

MD Sweeney, Z Zhao, A Montagne… - Physiological …, 2018 - journals.physiology.org
The blood-brain barrier (BBB) prevents neurotoxic plasma components, blood cells, and
pathogens from entering the brain. At the same time, the BBB regulates transport of …

Recent advancements of nanomedicine in neurodegenerative disorders theranostics

S Mukherjee, VS Madamsetty… - Advanced Functional …, 2020 - Wiley Online Library
Recent times have witnessed an upsurge in the incidence of neurodegenerative disorders
such as Alzheimer's disease, Parkinson's disease, Huntington's disease, Prion disease, and …

Blood–brain barrier and neurodegenerative diseases—modeling with iPSC-derived brain cells

YC Wu, TM Sonninen, S Peltonen, J Koistinaho… - International journal of …, 2021 - mdpi.com
The blood–brain barrier (BBB) regulates the delivery of oxygen and important nutrients to
the brain through active and passive transport and prevents neurotoxins from entering the …

Advances in nanomedicines for diagnosis of central nervous system disorders

X Zhang, J Zhou, Z Gu, H Zhang, Q Gong, K Luo - Biomaterials, 2021 - Elsevier
In spite of a great improvement in medical health services and an increase in lifespan, we
have witnessed a skyrocket increase in the incidence of central nervous system (CNS) …

Nanotechnology for neurodegenerative disorders

F Re, M Gregori, M Masserini - Maturitas, 2012 - Elsevier
The efficacy, cellular uptake and specific transport of drugs and/or imaging agents to target
organs, tissues and cells are common issues in the diagnosis and treatment of different …

RSM-CCD design of malachite green adsorption onto activated carbon with multimodal pore size distribution prepared from Amygdalus scoparia: Kinetic and isotherm …

R Bagheri, M Ghaedi, A Asfaram, EA Dil, H Javadian - Polyhedron, 2019 - Elsevier
In the present work, the activated carbon (AC) adsorbent with multimodal pore size
distribution prepared from Amygdalus scoparia as low-cost and locally available source was …

Blood-brain barrier dysfunction in CNS disorders and putative therapeutic targets: an overview

SR Archie, A Al Shoyaib, L Cucullo - Pharmaceutics, 2021 - mdpi.com
The blood-brain barrier (BBB) is a fundamental component of the central nervous system
(CNS). Its functional and structural integrity is vital to maintain the homeostasis of the brain …

[HTML][HTML] Transplantation of stem cell-derived astrocytes for the treatment of amyotrophic lateral sclerosis and spinal cord injury

C Nicaise, D Mitrecic, A Falnikar… - World journal of stem …, 2015 - ncbi.nlm.nih.gov
Neglected for years, astrocytes are now recognized to fulfill and support many, if not all,
homeostatic functions of the healthy central nervous system (CNS). During …

Increased surface P2X4 receptors by mutant SOD1 proteins contribute to ALS pathogenesis in SOD1-G93A mice

E Bertin, A Martinez, A Fayoux, K Carvalho… - Cellular and Molecular …, 2022 - Springer
Amyotrophic lateral sclerosis (ALS) is a fatal motoneuron (MN) disease characterized by
protein misfolding and aggregation leading to cellular degeneration. So far neither …

Breached barriers: a scoping review of blood-central nervous system barrier pathology in amyotrophic lateral sclerosis

A Mirian, A Moszczynski, S Soleimani… - Frontiers in Cellular …, 2022 - frontiersin.org
Introduction Recent studies have implicated changes in the blood-central nervous system
barriers (BCNSB) in amyotrophic lateral sclerosis (ALS). The objective of this scoping review …