Fluorescence lifetime imaging (FLIM) uses the fact that the fluorescence lifetime of a
fluorophore depends on its molecular environment but not on its concentration. Molecular …

The antioxidant system of the human body plays a crucial role in maintaining redox
homeostasis and has an important protective function. Carotenoids have pronounced …

Lymphedema is the clinical manifestation of impaired lymphatic transport. It remains an
under-recognized and under-documented clinical condition that still lacks a cure. Despite …

This article presents an overview of time-resolved (lifetime) fluorescence techniques used in
biomedical diagnostics. In particular, we review the development of time-resolved …

Clinical multiphoton tomography and two‐photon microendoscopy provide clinicians and
researchers with high‐resolution in vivo optical biopsies based on two‐photon …

In this review, the authors discuss the underlying principles of SHG and specific factors that
affect the generation properties and describe the essential components of a SHG instrument …

Age-related changes in skin mechanics have a major impact on the aesthetic perception of
skin. The link between skin microstructure and mechanics is crucial for therapeutic and …

Skin cancer is the most common form of cancer and is globally rising. Historically, the
diagnosis of skin cancers has depended on various conventional techniques which are of …

Second‐harmonic generation (SHG) microscopy is a fantastic tool for imaging collagen and
probing its hierarchical organization from molecular scale up to tissue architectural level. In …

We compare second harmonic generation (SHG) to histological and immunohistochemical
techniques for the visualization and scoring of collagen in biological tissues. We show that …