Myeloperoxidase: regulation of neutrophil function and target for therapy
SA Rizo-Téllez, M Sekheri, JG Filep - Antioxidants, 2022 - mdpi.com
Neutrophils, the most abundant white blood cells in humans, are critical for host defense
against invading pathogens. Equipped with an array of antimicrobial molecules, neutrophils …
against invading pathogens. Equipped with an array of antimicrobial molecules, neutrophils …
[HTML][HTML] Hypochlorous acid inactivates myeloperoxidase inside phagocytosing neutrophils
M Paumann-Page, LV Ashby, I Khalilova… - Redox Biochemistry and …, 2023 - Elsevier
When neutrophils phagocytose bacteria, they release myeloperoxidase (MPO) into
phagosomes to catalyse the conversion of superoxide to the potent antimicrobial oxidant …
phagosomes to catalyse the conversion of superoxide to the potent antimicrobial oxidant …
Sodium butyrate mitigates iE-DAP induced inflammation caused by high-concentrate feeding in liver of dairy goats
A Chandra Roy, Y Wang, H Zhang, S Roy… - Journal of agricultural …, 2018 - ACS Publications
The aim of this study is to explore the impact of sodium butyrate on d-glutamyl-meso-
diaminopimelic acid (iE-DAP)-induced liver inflammation in dairy goats during subacute …
diaminopimelic acid (iE-DAP)-induced liver inflammation in dairy goats during subacute …
The Mechanism of Elizabethkingia miricola Infection of the Black Spotted Frog as Revealed by Multi-Omics Analysis
Q Wei, D Wang, K Wei, B Xu, J Xu - Fishes, 2024 - mdpi.com
Elizabethkingia miricola (E. miricola) is a significant pathogen that causes the crooked head
disease in black spotted frogs. This disease has plagued numerous frog farms in China and …
disease in black spotted frogs. This disease has plagued numerous frog farms in China and …
Lactoferrin modified by hypohalous acids: Partial loss in activation of human neutrophils
DV Grigorieva, IV Gorudko, NA Grudinina… - International Journal of …, 2022 - Elsevier
Previously we have shown that lactoferrin (LTF), a protein of secondary neutrophilic
granules, can be efficiently modified by hypohalous acids (HOCl and HOBr), which are …
granules, can be efficiently modified by hypohalous acids (HOCl and HOBr), which are …
Impact of dual neutralization of TNF-α and IL-1β along with Gentamicin treatment on the functions of blood and splenic neutrophils and its role on improvement of S …
S Ghosh, R Ghosh, R Sawoo, P Dutta… - International …, 2023 - Elsevier
Researches of recent past years have emphasized potential of antibiotics to improve septic
arthritis but as multi-drug resistant strains like MRSA are emerging fast, new alternative …
arthritis but as multi-drug resistant strains like MRSA are emerging fast, new alternative …
Structure-biological activity relationships of myeloperoxidase to effect on platelet activation
Abstract Myeloperoxidase (MPO), an oxidant-producing enzyme of neutrophils, has been
shown to prime platelet activity promoting immunothrombosis. Native MPO is a homodimer …
shown to prime platelet activity promoting immunothrombosis. Native MPO is a homodimer …
Oxidation of cysteine by ceruloplasmin leads to formation of hydrogen peroxide, which can be utilized by myeloperoxidase
VA Kostevich, AV Sokolov - Biochemical and biophysical research …, 2018 - Elsevier
Myeloperoxidase (MPO) is the enzyme of azurophilic granules of neutrophils, which
catalyzes two electron oxidation of either chloride or bromide in the so-called “halogenating …
catalyzes two electron oxidation of either chloride or bromide in the so-called “halogenating …
[PDF][PDF] Redox Biochemistry and Chemistry
When neutrophils phagocytose bacteria, they release myeloperoxidase (MPO) into
phagosomes to catalyse the conversion of superoxide to the potent antimicrobial oxidant …
phagosomes to catalyse the conversion of superoxide to the potent antimicrobial oxidant …
Bioradical homeostasis as new complex parameters of different biological systems
AK Martusevich, AG Soloveva… - Journal of Integrated …, 2020 - jiomics.com
The current state of free radical biomedicine allows us to formulate a fundamentally new
parameter of homeostasis–bioradical homeostasis, understood as a state of free radical …
parameter of homeostasis–bioradical homeostasis, understood as a state of free radical …