Cellular DNA is continuously engaged in a molecular dance with many accessory proteins.
These proteins are responsible for orchestrating the storage, maintenance, and transfer of …

The genomes of all organisms throughout the tree of life are compacted and organized in
chromatin by association of chromatin proteins. Eukaryotic genomes encode histones, which …

High temperature is one of the major environmental stresses affecting plant growth and
fitness. Heat stress transcription factors (HSFs) play critical roles in regulating the expression …

Non-homologous end joining (NHEJ) is the primary pathway for repairing DNA double-
strand breaks (DSBs) in mammalian cells. Such breaks are formed, for example, during …

Bacteria frequently need to adapt to altered environmental conditions. Adaptation requires
changes in gene expression, often mediated by global regulators of transcription. The …

The archaeal genome is organized by either eukaryotic-like histone proteins or bacterial-like
nucleoid-associated proteins. Recent studies have revealed novel insights into chromatin …

Nucleoid‐associated protein HU, a conserved protein across eubacteria is necessary for
maintaining the nucleoid organization and global regulation of gene expression …

Nucleoid-associated proteins (NAPs) play a central role in chromosome organization and
environment-responsive transcription regulation. The Bacillus subtilis-encoded NAP Rok …

The CRISPR–Cas system for prokaryotic adaptive immunity provides RNA-mediated
protection from viruses and mobile genetic elements. Adaptation is dependent on the Cas1 …

Thermoacidophilic archaea belonging to the order Sulfolobales thrive in extreme biotopes,
such as sulfuric hot springs and ore deposits. These microorganisms have been model …